Advanced imaging techniques for eye conditions
Official title: High Resolution and High Speed Multimodal Ophthalmic Imaging
Run by Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts · NCT04129021 · Data updated 2026-11-12
This study is testing new advanced imaging techniques to see if they can help doctors better understand and diagnose eye diseases like retinitis pigmentosa and maculopathy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1200 (estimated) |
| Sponsor | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | July 3, 2019 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | November 18, 2025 |
| Trial ID | NCT04129021 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals over 18 with eye pathologies or healthy volunteers willing to participate.
✕Probably not a fit
Patients with a history of photosensitivity or those with certain medical devices or conditions that may interfere with imaging will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project focuses on utilizing high-resolution and high-speed multimodal imaging systems to enhance the visualization of microstructures in the eye, which are often undetectable with standard clinical imaging devices. By capturing detailed images of the retina and other ocular structures, the study aims to improve the understanding of various eye diseases, including retinitis pigmentosa and maculopathy. The project will compare the performance of these advanced imaging systems against existing technologies to identify the most effective techniques for future medical device development.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic capabilities and treatment options for patients with serious eye conditions.
How similar studies have gone: Other studies utilizing advanced imaging techniques have shown promise in enhancing the understanding and treatment of ocular diseases, indicating a positive trend in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * People over 18 * Patient with a pathology affecting the eye or healthy volunteer * Participant who signed the consent * Beneficiaries of the health insurance Exclusion Criteria: * Patients with a history of photosensitivity. * Patients who have just received a photodynamic therapy treatment ( * Patients taking drugs with photosensitivity as a side effect. * Persons with pacemakers or other implanted electronic medical device * Patients with viral conjunctivitis or any other infectious disease. * Patients with skin lesions on the neck or forehead * Patients at high risk of damage from optical radiation, such as aphakic patients, or patients with decreased sensitivity to light due to fundus disease. * Pregnant or lactating women * Participant unable to be followed throughout the study * Vulnerable people * Subjects with predisposition to closure of the iridocorneal angle
Where it's running
-
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Paris, France Recruiting
Study contacts
- Principal investigator: Michel PAQUES — Centre Hospitalier National d'Ophtalmologie des Quinze-Vints
- Study coordinator: Nabil BROUK
- Email: nbrouk@15-20.fr
- Phone: +33 140021144
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.