Condition

Primary Liver Cancer clinical trials and research

• 9Clinical trials
• 14Countries

Newest Primary Liver Cancer clinical trials

All recruiting trials (9)

• Plasma methylation test for detecting liver cancer recurrence (GNB4 and Riplet)

  This test sees if a blood-based methylation assay measuring GNB4 and Riplet can detect return of primary liver cancer in people who had hepatectomy, liver transplant, ablation, or TACE.

  Recruiting Wuhan Ammunition Life-tech Co., Ltd · Wuhan, Hubei · NCT07466602

• Using contrast-enhanced ultrasound to check Y-90 radioembolization response in liver cancer

  This will test whether contrast-enhanced ultrasound (CEUS) can show treatment response to Y‑90 radioembolization in people with newly diagnosed hepatocellular carcinoma who are scheduled for TARE.

  Recruiting Phase 2 Thomas Jefferson University · Philadelphia, Pennsylvania · NCT07145801

• Combining advanced ultrasound and molecular analyses to map tumor differences in liver cancer

  This project tries combining multiple ultrasound techniques with molecular (multi-omics) tests to see if they can better characterize tumors and guide care for adults with primary liver cancer who are scheduled for surgery.

  Recruiting Peking Union Medical College Hospital · Beijing · NCT07101237

• Combining portal and hepatic vein embolization for liver cancer treatment

  This study is testing if combining two types of vein treatments can help more people with liver cancer have surgery and live longer.

  Recruiting Maastricht University · New Haven, Connecticut and 54 other locations · NCT06914648

• Comparing two treatments for inoperable primary liver cancer

  This study is testing which treatment works better for people with inoperable primary liver cancer by comparing stereotactic radiosurgery and radiofrequency ablation.

  Recruiting Phase 2 Tianjin Medical University Cancer Institute and Hospital · Tianjin · NCT06766643

• Evaluation of the HistoSonics Edison System for treating liver tumors

  This study is testing how well the HistoSonics Edison System works for treating liver tumors and how different factors affect the treatment's success in real patients.

  Recruiting at 32 sites HistoSonics, Inc. · Mobile, Alabama and 34 other locations · NCT06486454

• Evaluating a protein as a marker for liver cancer recurrence

  This study is trying to see if higher levels of a certain protein in the blood can help predict if liver cancer will come back in people who have already had it.

  Recruiting Nanjing Medical University · Nanjing, Jiangsu · NCT06430983

• Liquid biopsy to differentiate types of primary liver cancer

  This study is testing a new blood test to see if it can tell the difference between two types of liver cancer, hepatocellular carcinoma and intrahepatic cholangiocarcinoma, to help doctors diagnose patients more safely.

  Recruiting at 5 sites City of Hope Medical Center · Duarte, California and 4 other locations · NCT06342414

• Evaluating liver embolization techniques for tumor management

  This study tests different liver embolization methods to see how well they help people with liver tumors live longer and maintain liver function while they continue their usual treatments.

  Recruiting IRCCS San Raffaele · Milan · NCT05714124

Related topics

Quick answers

How many Primary Liver Cancer clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in China (4 trials), United States (4 trials), Italy (2 trials), Australia (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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