Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating liver embolization techniques for tumor management

Official title: Liver Embolization Approaches for Tumor Management - Retrospective and Prospective Analysis of the Short-, Medium-, and Long-term Clinical Course of Patients Subjected to Embolization Treatment for Primary and Secondary Liver Neoplasms

Run by IRCCS San Raffaele · NCT05714124 · Data updated 2026-11-12

This study tests different liver embolization methods to see how well they help people with liver tumors live longer and maintain liver function while they continue their usual treatments.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment580 (estimated)
SponsorIRCCS San Raffaele
Academic / other
Locations1 site (Milan)
StatusRecruiting
StartedMay 21, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2031
Registry record updatedApril 12, 2024
Trial IDNCT05714124 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with primary or secondary liver tumors that are not suitable for surgery or ablation.

Probably not a fit

Patients with diffuse extrahepatic disease or those who are pregnant will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the short, medium, and long-term outcomes of various embolization techniques in patients with primary and secondary liver tumors. It focuses on assessing progression-free survival following embolization and the residual hepatic volume in cases where these techniques are used to promote liver regeneration. Patients will continue their standard treatment protocols without any additional interventions specific to the study.

Why it matters

Potential benefit: If successful, this study could provide insights into the most effective embolization techniques for managing liver tumors, potentially improving patient outcomes.

How similar studies have gone: Other studies have explored embolization techniques for liver tumors, indicating a growing body of evidence, though this specific observational approach may provide novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 18 yoa
* patients with patients with primary or secondary liver disease not amenable for surgery or ablation
* patients with primary or secondary liver tumors candidates for major surgery prior to induction of hypertrophy
* able and willing to sign informed consent

Exclusion Criteria:

* pregnant women
* patients with uncorrectable coagulopathy
* diffuse extrahepatic disease
* for lobar TACE and TARE - presence of bilodigestive shunt
* for TARE - \>20% hepatopulmonary shunt

Where it's running

  • IRCCS Ospedale San Raffaele
    Milan, Italy
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.