Clinical trial Recruiting at 1 site Observational Ages 18 to 75

Evaluating a protein as a marker for liver cancer recurrence

Official title: Recurrent Liver Cancer: Reconceptualization and Reevaluation

Run by Nanjing Medical University · NCT06430983 · Data updated 2026-11-12

This study is trying to see if higher levels of a certain protein in the blood can help predict if liver cancer will come back in people who have already had it.

Quick facts

Study typeObservational
Ages18 Years to 75 Years
SexAll
Enrollment300 (estimated)
SponsorNanjing Medical University
Academic / other
Locations1 site (Nanjing, Jiangsu)
StatusRecruiting
StartedJuly 1, 2024
Main results expectedAugust 1, 2026
Study endsOctober 1, 2027
Registry record updatedDecember 12, 2024
Trial IDNCT06430983 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients diagnosed with recurrent or primary liver cancer who can provide informed consent and blood samples.

Probably not a fit

Patients who are pregnant, have received organ transplants, or have other tumors may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine if elevated levels of a specific protein can indicate the recurrence of liver cancer. It will compare 50 recurrent liver cancer patients with 250 additional recurrent liver cancer patients to assess the protein's levels against those of primary liver cancer patients. The study will collect clinical data, including demographics and medical history, while implementing strict quality control measures to ensure data reliability. Participants will provide blood samples for analysis, and the study has received ethical approval.

Why it matters

Potential benefit: If successful, this study could provide a new biomarker for the early detection of liver cancer recurrence, improving patient monitoring and outcomes.

How similar studies have gone: While the approach of using biomarkers for cancer recurrence is common, the specific protein being evaluated in this study may represent a novel focus that has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with primary hepatocellular carcinoma or diagnosed with non-HCC
* The patient or the patient's legal representative must be able to read, understand, and sign the informed consent form
* Agree to provide blood samples and have good clinical compliance
* Complete clinical basic information, including: the patient's unique traceability number (ID card number/outpatient number/health insurance card number), age, gender, imaging and/or pathological diagnosis results (for patients with primary liver disease), imaging examination confirmed heteromorphic liver cancer (for non-HCC patients)

Exclusion Criteria:

* Pregnant women
* Those who have received organ transplantation
* Non-HCC patients diagnosed with other tumors
* Patients with primary hepatocellular carcinoma complicated by other tumors
* Those judged by the researcher as not meeting the inclusion criteria

Where it's running

  • The Second Affiliated Hospital of Nanjing Medical University
    Nanjing, Jiangsu, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.