Condition

Primary Dysmenorrhea clinical trials and research

• 13Clinical trials
• 2NIH research projects
• 7Countries

Newest Primary Dysmenorrhea clinical trials

All recruiting trials (13)

• Virtual reality for reducing pain and anxiety in women with menstrual cramps

  In women with primary dysmenorrhea, this study tests whether a relaxing virtual reality experience can lower pain and anxiety during a 3-day period.

  Recruiting at 2 sites Tokat Gaziosmanpasa University · Erbaa, Tokat Province and 1 other locations · NCT07853508

• Connective Tissue Massage and Music-based Relaxation for Period Pain

  This study tests whether connective tissue massage or a music-based relaxation program can reduce pain and related symptoms in young women with primary dysmenorrhea.

  Recruiting Pamukkale University · Denizli · NCT07647276

• Structured yoga for young women with primary dysmenorrhea

  This study tests whether a guided yoga program can help reduce menstrual pain and improve quality of life in 18–25 year-old women with primary dysmenorrhea.

  Recruiting Ankara University · Ankara · NCT07520136

• Self-acupressure to reduce period pain and premenstrual symptoms

  This trial will test whether a self-acupressure routine can reduce period pain and premenstrual symptoms in university students aged 18–30 with primary dysmenorrhea.

  Recruiting Nigde Omer Halisdemir University · Niğde, Merkez · NCT07409337

• Ankle (posterior tibial) nerve stimulation for primary menstrual cramps

  This test tries gentle electrical stimulation of the posterior tibial nerve at the ankle to reduce menstrual cramp pain in women with primary dysmenorrhea aged 20–25.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh, Kafrelsheikh · NCT07352982

• Knee position sense and balance in women with primary dysmenorrhea

  This test looks at whether primary menstrual cramps affect knee joint position sense, pain levels, and dynamic balance in healthy 18–25-year-old women.

  Recruiting Cairo University · Giza · NCT07239232

• How primary menstrual cramps affect abdominal and back muscle activity in young women

  This will test whether menstrual cramps from primary dysmenorrhea change the electrical activity of the abdominal and back muscles in women aged 18 to 25.

  Recruiting Cairo University · Giza · NCT07095725

• Chamomile and L-theanine beverage for menstrual pain in young women

  This will test whether a chamomile and L-theanine drink can reduce menstrual pain and improve mood and sleep in young women with primary dysmenorrhea.

  Recruiting Universiti Tunku Abdul Rahman · Kampar, Perak · NCT07092878

• Botulinum toxin injected into the uterine muscle to reduce severe menstrual pain

  This trial will test whether a single botulinum toxin injection into the uterine wall via hysteroscopy can reduce severe menstrual cramps in women who did not get relief from first-line hormonal and pain treatments, compared with a placebo injection.

  Recruiting at 7 sites Phase 3 Nantes University Hospital · Aix-en-Provence and 7 other locations · NCT06995287

• Kegel exercises and myokinetic release for menstrual pain relief

  This study is testing whether Kegel exercises or a different technique called myokinetic release can help young women aged 17-25 feel less menstrual pain and improve their quality of life.

  Recruiting at 2 sites Riphah International University · Lahore, Punjab Province and 1 other locations · NCT06777940

• Cognitive exercise therapy and yoga for period pain in teen girls

  This study will test whether cognitive exercise therapy or yoga can reduce menstrual pain and improve function in adolescent girls with primary dysmenorrhea.

  Recruiting Acibadem University · Istanbul, Ataşehir · NCT06398990

• Dry needling for menstrual pain relief

  This study is testing whether dry needling can help young women with painful periods feel better compared to traditional acupuncture and a placebo.

  Recruiting at 2 sites Beijing Hospital · Beijing, Beijing Municipality and 1 other locations · NCT06316583

• CDE100 for menstrual cramp pain in primary dysmenorrhea

  We will see if CDE100 reduces menstrual cramp pain in people aged 16 to 35 with primary dysmenorrhea.

  Recruiting Phase 3 Ems · Hortolândia, São Paulo · NCT05640232

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Gut microbiome and multisensory sensitivity in teen menstrual pain

  A study in adolescent girls with moderate-to-severe menstrual pain will explore how gut bacteria relate to their pain and sensitivity to different senses.

  NIH research Mclean Hospital · Belmont, United States · NIH-11438140

• Understanding menstrual pain and its effects on adolescent girls

  This study is looking at menstrual pain in girls aged 14-18 to find out what might predict if they will develop long-lasting pain, using tests and brain scans to understand how their bodies handle pain, with the hope of improving treatment options in the future.

  NIH research Mclean Hospital · Belmont, United States · NIH-10624359

Related topics

Quick answers

How many Primary Dysmenorrhea clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Turkey (Türkiye) (5 trials), Egypt (3 trials), China (1 trial), Malaysia (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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