Cognitive exercise therapy and yoga for period pain in teen girls

The Effect of Telerehabilitation-Based Cognitive Exercise Therapy Approach and Yoga on Pain, Physical Function and Quality of Life in Adolescents With Dysmenorrhoea

Not applicable Interventional Acibadem University · NCT06398990

This study will test whether cognitive exercise therapy or yoga can reduce menstrual pain and improve function in adolescent girls with primary dysmenorrhea.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment42 (estimated)
Ages10 Years to 19 Years
SexFemale
SponsorAcibadem University Academic / other
Locations1 site (Istanbul, Ataşehir)
Trial IDNCT06398990 on ClinicalTrials.gov

What this trial studies

This is a prospective, randomized, controlled, parallel-group trial comparing three arms: cognitive exercise therapy, yoga, and routine medical treatment in adolescents with primary dysmenorrhea. About 36 participants are planned for analysis (target enrollment ~42 to allow for dropouts), with measurements taken at three time points to track pain, physical function, and quality of life. Participants are randomized to one of the three groups to reduce bias and ensure comparability. Outcomes focus on menstrual pain intensity (VAS) and related functional and quality-of-life measures.

Who should consider this trial

Good fit: Adolescent females aged 10–19 with at least 6–12 months of menstruation, diagnosed primary dysmenorrhea, VAS pain ≥4, nulliparous, able to read Turkish, and willing to provide consent are ideal candidates.

Not a fit: Girls with suspected or confirmed secondary dysmenorrhea, serious comorbid medical or psychiatric conditions, recent abdominal/pelvic/spinal surgery, current pregnancy, or use of conflicting treatments are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, these non-drug, mind-body approaches could reduce menstrual pain and improve school performance and quality of life for adolescent girls.

How similar studies have performed: Previous studies of yoga and other mind-body interventions have reported large reductions in menstrual pain, but evidence in adolescent populations is limited and not yet definitive.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Between the ages of 10 and 19,
* Having had a menstrual cycle for at least 6-12 months (ACOG, 2018),
* Having menstrual pain intensity of ≥4 cm according to the Visual Analog Scale (VAS, 0-10 cm) (Kannan, P. 2015; Yonglitthipagon, P. 2017),
* To have been diagnosed with primary dysmenorrhea according to the clinical characteristics and diagnostic approach defined in international dysmenorrhea guidelines (ACOG 2018; JOGC 2017),
* Nulliparous (having never given birth),
* Able to read and write in Turkish,
* Willing to participate in the study and having provided informed consent.

Exclusion Criteria:

* History or clinical findings suggestive of secondary dysmenorrhea,
* Presence of serious comorbidities, including neurological, cardiovascular, musculoskeletal, psychiatric, gastrointestinal, or autoimmune disorders,
* History of surgery involving the abdominal, pelvic, or spinal regions within the past 12 months,
* Current pregnancy or suspected pregnancy,
* Use of intrauterine devices (IUDs),
* Current or recent participation in cognitive exercise therapy and/or yoga interventions,
* Concurrent participation in another clinical study.

Where this trial is running

Istanbul, Ataşehir

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DysmenorrheaPrimary Dysmenorrheadysmenorrheamind-body exercisescognitive exercise therapy approachyoga
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.