Understanding menstrual pain and its effects on adolescent girls

Behavioral and Neural Phenotypes of Primary Dysmenorrhea in Adolescents

NIH-funded research Mclean Hospital · NIH-10624359

This study is looking at menstrual pain in girls aged 14-18 to find out what might predict if they will develop long-lasting pain, using tests and brain scans to understand how their bodies handle pain, with the hope of improving treatment options in the future.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMclean Hospital NIH-funded
Lab location1 site (Belmont, United States)
Project IDNIH-10624359 on NIH RePORTER

What this research studies

This research investigates primary dysmenorrhea, a type of menstrual pain experienced by adolescent girls aged 14-18. It aims to identify biomarkers and brain characteristics that may predict the development of chronic pain. Participants will undergo various assessments, including pain sensitivity tests and advanced brain imaging techniques, to explore how their pain experiences are processed in the brain. The goal is to uncover mechanisms that could lead to better prevention and treatment strategies for those at risk of chronic pain.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescent girls aged 14-18 who experience menstrual pain.

Not a fit: Patients outside the age range of 14-18 or those without menstrual pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to targeted treatments that prevent chronic pain in adolescent girls.

How similar studies have performed: Previous research has shown promise in identifying pain biomarkers in similar populations, suggesting potential for success in this approach.

Where this research is happening

Belmont, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.