Clinical trial Recruiting at 1 site Interventional Ages 18 to 30 Women only

Self-acupressure to reduce period pain and premenstrual symptoms

Official title: Effects of Self-Acupressure on Primary Dysmenorrhea and Premenstrual Symptoms in Women Aged 18-30: A Randomized, Sham-Controlled, 6-Month Trial

Run by Nigde Omer Halisdemir University · NCT07409337 · Data updated 2026-11-12

This trial will test whether a self-acupressure routine can reduce period pain and premenstrual symptoms in university students aged 18–30 with primary dysmenorrhea.

More Primary Dysmenorrhea trials

Quick facts

Study typeInterventional
Ages18 Years to 30 Years
SexWomen only
Enrollment120 (estimated)
SponsorNigde Omer Halisdemir University
Academic / other
Locations1 site (Niğde, Merkez)
StatusRecruiting
StartedFebruary 15, 2026
Main results expectedDecember 15, 2026
Study endsDecember 15, 2026
Registry record updatedAugust 24, 2026
Trial IDNCT07409337 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are female university students aged 18–30 with regular 21–35 day cycles, moderate to severe primary dysmenorrhea and PMS, not using hormonal contraception, and willing to perform self-acupressure for about six cycles.

Probably not a fit

Patients with secondary causes of menstrual pain (for example endometriosis or fibroids), current or recent hormonal therapy, pregnancy/breastfeeding, chronic systemic illnesses, or prior formal acupuncture/acupressure training are unlikely to benefit from this protocol or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, parallel-group, sham-controlled trial comparing a self-administered acupressure protocol applied to predefined points (SP6, CV4, ST36, LV3) with a matched sham acupressure applied to non-acupoint locations. Participants are university students aged 18–30 with regular cycles who will perform daily acupressure during the premenstrual phase and early menstruation across about five to six cycles. Primary outcome is change in menstrual pain severity, with secondary outcomes including premenstrual symptom scores, analgesic use, and menstruation-related activity limitation. Interventions are matched for training, session duration, frequency, and pressure intensity to isolate the specific effects of acupoint stimulation.

Why it matters

Potential benefit: If effective, this low-cost, self-administered method could reduce menstrual pain and premenstrual symptoms without medication.

How similar studies have gone: Previous small randomized studies of acupuncture and acupressure for dysmenorrhea have shown mixed but often promising results, so the approach has prior supportive but not definitive evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female participants aged 18 to 30 years
* Regular menstrual cycles (21-35 days)
* Diagnosis of primary dysmenorrhea with moderate to severe menstrual pain
* Presence of premenstrual symptoms consistent with premenstrual syndrome
* Currently enrolled as a university student
* Willingness to perform self-acupressure as instructed for approximately six menstrual cycles
* Ability to understand the study procedures and provide written informed consent

Exclusion Criteria:

* Secondary dysmenorrhea (e.g., endometriosis, uterine fibroids, pelvic inflammatory disease)
* Current use of hormonal contraceptives or hormonal therapy within the past 3 months
* Pregnancy or breastfeeding
* Chronic gynecological, endocrine, or systemic disease that may affect menstrual pain or symptoms
* Regular use of analgesic or anti-inflammatory medications outside menstruation
* Prior formal training or regular practice of acupuncture or acupressure
* Inability to comply with study procedures or follow-up schedule

Where it's running

  • Niğde Ömer Halisdemir University Hospital
    Niğde, Merkez, Turkey (Türkiye)
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.