Condition
Polysubstance Abuse clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Polysubstance Abuse clinical trials that are recruiting, at sites in 2 countries (most in United States (3), Canada (1)). By phase: Phase 2 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Polysubstance Abuse clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Canadian Emergency Department Opioid Registry (CEDRN) | — | Vancouver, British Columbia | Recruiting | Mar 12, 2026 |
| Using motivational interviewing and mindfulness to help reduce substance use | Phase 3 | New Brunswick, New Jersey and 1 other locations | Recruiting | Sep 13, 2023 |
| Investigating the effects of opioids and benzodiazepines on substance abuse | Phase 2 | Detroit, Michigan | Recruiting | Aug 16, 2021 |
| Understanding opioid and benzodiazepine abuse patterns | — | Detroit, Michigan | Recruiting | Oct 4, 2018 |
All recruiting trials (4)
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Canadian Emergency Department Opioid Registry (CEDRN)
This project will create a national emergency department registry to collect information on people of all ages who come to EDs with suspected or confirmed opioid poisoning to see if those data can guide better care and prevent deaths.
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Using motivational interviewing and mindfulness to help reduce substance use
This study is testing whether combining motivational interviewing and mindfulness techniques can help people who struggle with using multiple substances, like opioids and tobacco, to reduce their use.
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Investigating the effects of opioids and benzodiazepines on substance abuse
This study is trying to see how using opioids and benzodiazepines together affects emotions and decision-making in people who have struggled with substance abuse.
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Understanding opioid and benzodiazepine abuse patterns
This study is trying to understand how people being treated for Substance Use Disorder in Wayne County use both opioids and benzodiazepines together, to see if this can help improve their treatment.
Related topics
Quick answers
How many Polysubstance Abuse clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (3 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.