Condition

Opioid Withdrawal clinical trials and research

• 7Clinical trials
• 2Countries

Newest Opioid Withdrawal clinical trials

All recruiting trials (7)

• Canadian Emergency Department Opioid Registry (CEDRN)

  This project will create a national emergency department registry to collect information on people of all ages who come to EDs with suspected or confirmed opioid poisoning to see if those data can guide better care and prevent deaths.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT07466784

• Sparrow Link device to help with opioid withdrawal in hospitalized adults with OUD

  A wearable nerve-stimulation device is being tested to see if it can help reduce withdrawal symptoms in adults with opioid use disorder who are hospitalized and receiving standard care.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07079826

• Measuring physiological symptoms during opioid withdrawal and cravings

  This study is testing how the body reacts during opioid withdrawal and cravings in people with opioid dependence by using smartwatches to track their heart rate, skin temperature, and other signals over two weeks.

  Recruiting Spark Biomedical, Inc. · Center City, Minnesota and 1 other locations · NCT06487533

• Improving outcomes for chronic pain patients on long-term opioid therapy

  This study is testing three new ways to help people with chronic pain who are using long-term opioid therapy feel better and improve their quality of life.

  Recruiting Phase 1/2 Medical University of South Carolina · Charleston, South Carolina · NCT06442566

• Using ear stimulation to treat chronic pain and opioid withdrawal

  This study is testing whether a device that stimulates nerves around the ear can help people with chronic pain and those going through opioid withdrawal feel better.

  Recruiting The University of Texas Medical Branch, Galveston · Galveston, Texas · NCT05555485

• Using buspirone to help with opioid withdrawal

  This study is testing if the medication buspirone can help people with opioid use disorder feel less withdrawal symptoms and cravings while they are tapering off opioids.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT05511909

• Evaluating opioid withdrawal symptoms during medication tapering

  This study is testing how different people experience withdrawal symptoms when they slowly reduce their opioid use under medical supervision to help improve treatment for opioid use disorder.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT05027919

Related topics

Quick answers

How many Opioid Withdrawal clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (6 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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