Using motivational interviewing and mindfulness to help reduce substance use
Official title: Motivational Interviewing (MI) and Mindfulness-Oriented Recovery Enhancement (MORE) for Tobacco Dependence and Other Drug Use in Methadone Treatment
Run by Rutgers, The State University of New Jersey · NCT06033599 · Data updated 2026-11-12
This study is testing whether combining motivational interviewing and mindfulness techniques can help people who struggle with using multiple substances, like opioids and tobacco, to reduce their use.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 420 (estimated) |
| Sponsor | Rutgers, The State University of New Jersey Academic / other |
| Locations | 2 sites (New Brunswick, New Jersey and 1 other locations) |
| Status | Recruiting |
| Started | September 5, 2023 |
| Main results expected | June 2028 |
| Study ends | August 2028 |
| Registry record updated | July 17, 2026 |
| Trial ID | NCT06033599 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are English-speaking adults aged 18 and older who are currently on methadone and smoke cigarettes.
✕Probably not a fit
Patients with severe cognitive impairment, psychosis, or those who are currently pregnant or breastfeeding may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to explore the implementation of Motivational Interviewing (MI) and Mindfulness-Oriented Recovery Enhancement (MORE) for individuals struggling with polysubstance abuse, particularly focusing on opioid and tobacco use. It will assess barriers and facilitators to the adoption of these interventions in clinical settings while also evaluating their effectiveness in reducing substance use among participants. The study will involve various treatment groups, including those receiving MI and MORE, as well as support groups, to determine the best approach for patient outcomes.
Why it matters
Potential benefit: If successful, this study could provide effective strategies for reducing substance use and improving recovery outcomes for individuals with polysubstance abuse issues.
How similar studies have gone: Other studies have shown promise in using motivational interviewing and mindfulness techniques for substance use treatment, indicating that this approach has potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * English-speaking * Age ≥18 * Currently on methadone; and 4) currently smoke cigarettes. Exclusion Criteria: * Severe cognitive impairment (score \>23 on Mini Mental Status Exam) or psychosis (positive SCID Psychotic Screen) * Suicidal risk (score ≥7 on Suicidal Behaviors Questionnaire) * Inability to attend or fully participate in intervention sessions or assessments * Previous formal mindfulness training (e.g., MBSR, MBRP) or MORE (from the R21 or R33 * Currently taking smoking cessation pharmacotherapy or participating in smoking cessation counseling * Any contraindications for NRT * Currently or soon planning to be pregnant or breastfeeding.
Where it's running
-
Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey, United States Recruiting -
University of Utah
Salt Lake City, Utah, United States Recruiting
Study contacts
- Principal investigator: Nina Cooperman, PsyD — Rutgers Robert Wood Johnson Medical School
- Study coordinator: Nina Cooperman, PsyD
- Email: cooperna@rwjms.rutgers.edu
- Phone: 732-235-8569
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.