Understanding opioid and benzodiazepine abuse patterns
Opioid/Benzodiazepine Polydrug Abuse: Integrating Research on Mechanisms, Treatment and Policies
Wayne State University · NCT03696017
This study is trying to understand how people being treated for Substance Use Disorder in Wayne County use both opioids and benzodiazepines together, to see if this can help improve their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Wayne State University (other) |
| Locations | 1 site (Detroit, Michigan) |
| Trial ID | NCT03696017 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the patterns of polysubstance abuse involving opioids and benzodiazepines among patients currently undergoing treatment for Substance Use Disorder in Wayne County. Up to 120 participants will undergo a comprehensive 6-hour assessment that includes clinical evaluations and hypothesis-driven measures related to mental health and substance use. The study will utilize various assessment tools, including interviews and questionnaires, to gather data on affective dysregulation, neurocognition, and substance use behaviors. The findings may help identify phenotypes that could be targeted to reduce the risks associated with polysubstance abuse.
Who should consider this trial
Good fit: Ideal candidates are individuals recently admitted to treatment for Substance Use Disorder who are using opioids, benzodiazepines, or both.
Not a fit: Patients with severe psychiatric disorders, such as current psychosis or bipolar disorder, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients struggling with polysubstance abuse, potentially reducing overdose risks and improving outcomes.
How similar studies have performed: While there is limited data on this specific approach, previous studies have highlighted the dangers of polysubstance abuse, indicating a need for further investigation in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Recently admitted and/or not clinically stable in treatment for Substance Use Disorder (SUD) in Wayne County * Using opioids, benzodiazepines (BZD), or BZD/opioid. Exclusion Criteria: * Participants with current psychosis, bipolar disorder, or severe depression (i.e. severe psychiatric disorder) * Individuals with serious neurological disorders, e.g. brain tumor, history of stroke, history of traumatic brain injury w/ loss of consciousness * Cognitive impairment (IQ\<80)
Where this trial is running
Detroit, Michigan
- Tolan Park Medical Building — Detroit, Michigan, United States (RECRUITING)
Study contacts
- Principal investigator: Mark Greenwald, PhD — Wayne State University
- Study coordinator: Heidi Aguas
- Email: gh7962@wayne.edu
- Phone: 3139933960
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Polysubstance Abuse, Opioid Abuse, Benzodiazepine abuse