Condition

Peritoneal Carcinomatosis clinical trials and research

• 26Clinical trials
• 1NIH research projects
• 13Countries

Newest Peritoneal Carcinomatosis clinical trials

All recruiting trials (26)

• Repeated PIPAC plus standard platinum–taxane chemotherapy for advanced ovarian cancer with peritoneal spread

  This test sees if adding repeated cisplatin-based PIPAC to standard platinum–taxane chemotherapy helps women aged 18–75 with newly diagnosed FIGO IIIB–IIIC epithelial ovarian cancer and visible peritoneal carcinomatosis.

  Recruiting Phase 2 Moscow Regional Oncological Dispensary · Balashikha · NCT07514494

• Enhanced Recovery After Surgery for adults with peritoneal carcinomatosis undergoing cytoreductive surgery with or without HIPEC

  This project will try an Enhanced Recovery After Surgery (ERAS) program to see if it shortens hospital stays after cytoreductive surgery with or without HIPEC for adults with peritoneal carcinomatosis.

  Recruiting Fondazione del Piemonte per l'Oncologia · Candiolo, Turin and 1 other locations · NCT07493876

• PIPAC with Mitomycin C for unresectable peritoneal cancer

  This phase 1 study tests a breathy, pressurized chemotherapy method (PIPAC-MMC) to see if it is safe and tolerable for adults with unresectable peritoneal carcinomatosis from colorectal, appendiceal, or small bowel cancers.

  Recruiting Phase 1 H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT07487168

• Heated versus aerosolized chemotherapy delivered into the abdomen for cancer that has spread to the peritoneum

  This study will test whether heated (HIPEC) or aerosolized (PIPAC) mitomycin-based chemotherapy given into the abdomen works better and is safer for adults whose cancer has spread to the peritoneum.

  Recruiting Phase 2 Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Pittsburgh, Pennsylvania · NCT07282834

• Adding paclitaxel into the abdominal cavity for gastric cancer that has spread to the peritoneum

  This trial will try adding paclitaxel delivered directly into the abdomen to standard IV chemotherapy for people with gastric or gastroesophageal junction cancer that has spread to the lining of the abdominal cavity to see if it slows disease growth and helps them live longer.

  Recruiting at 78 sites Phase 2/3 Eastern Cooperative Oncology Group · Irvine, California and 77 other locations · NCT07001748

• Blood clearance of nucleosomes and CTCF after surgery for colorectal cancer with peritoneal spread

  This test will see if blood levels of nucleosomes and CTCF can indicate whether adults with colorectal cancer that has spread to the peritoneum have had all visible tumor removed by cytoreductive surgery.

  Recruiting Hospices Civils de Lyon · Pierre-Bénite · NCT06929013

• Mesothelin-targeted CAR T-cell therapy for esophagogastric cancer

  This study is testing a new treatment that uses modified immune cells to target and attack tumors in people with advanced esophagogastric cancer.

  Recruiting at 7 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT06623396

• Using pafolacianine for imaging during surgery for gastrointestinal cancer

  This study is testing if a special imaging drug called pafolacianine can help doctors find cancer spots better during surgery for adults with gastrointestinal cancer.

  Recruiting Early Phase 1 University of California, Irvine · Orange, California · NCT06511037

• Evaluating Radspherin® for Advanced Epithelial Cancer with Peritoneal Metastasis

  This study is testing a new treatment called Radspherin® to see if it can help people with advanced ovarian or related cancers that have spread in the abdomen feel better and improve their chances after surgery.

  Recruiting at 10 sites Phase 2 Oncoinvent Solutions AS · Tampa, Florida and 9 other locations · NCT06504147

• Using Ga68-FAPI-46 PET/CT to assess peritoneal carcinomatosis before surgery

  This study is testing a new type of imaging scan to see if it can better detect cancer spread in the abdomen before surgery for people with colorectal and ovarian cancer.

  Recruiting Jules Bordet Institute · Brussels · NCT06061874

• Modified early post-operative intraperitoneal chemotherapy for cancer treatment

  This study is testing a new way of giving chemotherapy right after surgery to see if it works better and is safer for people with cancer that has spread in the abdomen.

  Recruiting Phase 2 Ciusss de L'Est de l'Île de Montréal · Montreal, Quebec · NCT05913674

• Creating a model using patient samples for gastrointestinal cancer research

  This study is trying to create a model using samples from patients with gastrointestinal cancer to better understand the disease and find better treatments.

  Recruiting University of California, Irvine · Orange, California · NCT05844865

• Predicting responses to chemotherapy in gastrointestinal cancer using organoids

  This study is testing if lab-grown mini tumors from patients with gastric or colon cancer can help doctors find the best chemotherapy drugs to improve treatment outcomes.

  Recruiting at 4 sites Technische Universität Dresden · Berlin and 4 other locations · NCT05652348

• Assessing HIPEC with Mitomycin C for Colon Cancer with Peritoneal Metastases

  This study is testing if a heated chemotherapy treatment called HIPEC with Mitomycin C can help people with colon cancer that has spread to the abdominal lining do better after surgery.

  Recruiting at 28 sites Phase 4 Hospital Universitario de Fuenlabrada · Elche, Alicante and 30 other locations · NCT05250648

• Personalized chemotherapy for abdominal cancer treatment

  This study is testing a new way to personalize chemotherapy for patients with abdominal cancer by trying different treatments on their tumor samples before using them during surgery.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04847063

• Combination therapy for gastric cancer with inoperable bowel obstruction

  This study is testing a combination of three cancer drugs to see if it can help people with gastric cancer and a blocked bowel feel better and improve their condition.

  Recruiting Phase 2 Sixth Affiliated Hospital, Sun Yat-sen University · Guangzhou, Guangdong · NCT04840264

• Combination of PIPAC and systemic chemotherapy for advanced ovarian cancer

  This study is testing a new way to give chemotherapy for women with advanced ovarian cancer who haven't responded well to previous treatments, by combining a special spray method with regular chemotherapy to see how safe it is and what the best dose is.

  Recruiting at 6 sites Phase 1 Hospices Civils de Lyon · Lille and 5 other locations · NCT04811703

• Comparing flat dose and weight-based chemotherapy for peritoneal carcinomatosis

  This study is testing whether giving a flat dose or a dose based on body weight of a chemotherapy drug can help people with certain cancers that have spread to the abdominal area do better after surgery.

  Recruiting at 2 sites Phase 2 University of Kentucky · Lexington, Kentucky and 1 other locations · NCT04779554

• Aerosol chemotherapy for advanced gastric cancer treatment

  This study is testing a new way of delivering chemotherapy directly to tumors in people with advanced stomach cancer to see if it helps them live longer and feel better compared to standard treatment.

  Recruiting St. Petersburg State Pavlov Medical University · Saint Petersburg · NCT04595929

• Surgery and chemotherapy for gastric cancer with peritoneal spread

  This study is testing if a combination of surgery and specific chemotherapy can help people with advanced stomach cancer that has spread to the lining of the abdomen feel better and control their disease for at least six months.

  Recruiting National Taiwan University Hospital · Taipei · NCT04547725

• Using pressurized aerosol chemotherapy to treat advanced abdominal cancers

  This study is testing a new way to deliver chemotherapy directly into the abdomen using a special aerosol spray to see if it helps people with advanced abdominal cancers feel better and have fewer side effects.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Duarte, California and 2 other locations · NCT04329494

• Study on the effects of surgery and HIPEC for peritoneal carcinomatosis

  This study is testing how surgery and a special type of heated chemotherapy can affect the immune system and gut bacteria in people with peritoneal carcinomatosis to see how it impacts their health and recovery.

  Recruiting University of Regensburg · Regensburg, Bavaria and 1 other locations · NCT04108936

• Effects of heated chemotherapy on advanced gastric cancer

  This study is testing if a special heated chemotherapy treatment can help people with advanced gastric cancer feel better by boosting their immune response more than regular chemotherapy.

  Recruiting Phase 2 University of Chicago · Chicago, Illinois · NCT04107077

• Using cardiac coherence to reduce anxiety in patients with peritoneal carcinosis before surgery

  This study is testing if teaching patients with peritoneal carcinosis some breathing techniques can help reduce their anxiety before surgery.

  Recruiting Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier, Hérault · NCT04024917

• Pressurized Chemotherapy for High Risk Colon Cancer Patients

  This study is testing a new type of chemotherapy for patients with high-risk colon cancer to see if it can help prevent cancer from coming back after surgery and standard treatment.

  Recruiting Phase 2 Odense University Hospital · Odense · NCT03280511

• Registering patients undergoing heated chemotherapy for peritoneal cancers

  This study is collecting information from patients with certain abdominal cancers who are having surgery followed by heated chemotherapy to see if it helps them live longer and feel better.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Flemish Brabant · NCT01617382

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• A new model to study the spread of deadly colorectal and gastric cancers.

  This study is creating a special lab model to learn more about how cancer spreads in the abdomen, which could help improve treatments for patients with colorectal and gastric cancer.

  NIH research University of California-Irvine · Irvine, United States · NIH-11094078

Related topics

Quick answers

How many Peritoneal Carcinomatosis clinical trials are recruiting right now?

26, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (11 trials), Belgium (3 trials), France (3 trials), Germany (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 8, Phase 1: 5, Early Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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