Creating a model using patient samples for gastrointestinal cancer research
Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis
NA · University of California, Irvine · NCT05844865
This study is trying to create a model using samples from patients with gastrointestinal cancer to better understand the disease and find better treatments.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of California, Irvine (other) |
| Locations | 1 site (Orange, California) |
| Trial ID | NCT05844865 on ClinicalTrials.gov |
What this trial studies
This pilot study aims to collect and utilize samples from patients diagnosed with gastrointestinal peritoneal carcinomatosis. Participants will provide blood, ascites/peritoneal wash fluid, and tumor samples during their scheduled surgical procedures. The goal is to develop a patient-derived vascularized microtumor model that can help in understanding the disease better and potentially lead to improved treatment strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have a gastrointestinal tumor and are scheduled for a standard surgical procedure.
Not a fit: Patients who are unable to comply with the study protocol or do not have a gastrointestinal tumor will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of gastrointestinal peritoneal carcinomatosis and lead to more effective treatment options for patients.
How similar studies have performed: While this approach is innovative, similar studies utilizing patient-derived models have shown promise in other cancer types, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients must have a GI tumor * Must have planned standard of care surgical procedure * Age ≥ 18 years. * Ability to understand and the willingness to sign a written informed consent Exclusion Criteria: \- Pattens who are unable to comply with the study protocol
Where this trial is running
Orange, California
- Chao Family Comprehensive Cancer Center, University of California, Irvine — Orange, California, United States (RECRUITING)
Study contacts
- Principal investigator: Maheswari Senthil, MD FACS — Chao Family Comprehensive Cancer Center
- Study coordinator: Chao Family Comprehensive Cancer Center University of California, Irvine
- Email: ucstudy@uci.edu
- Phone: 1-877-827-7883
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Peritoneal Carcinomatosis, Gastrointestinal Peritoneal Carcinomatosis