Condition

Pelvic Organ Prolapse clinical trials and research

• 19Clinical trials
• 5NIH research projects
• 16Countries

Newest Pelvic Organ Prolapse clinical trials

All recruiting trials (19)

• Improving Uroflowmetry: Do Pre-Procedure Reminders Help Women Undergoing Urodynamics

  This study tests whether sending reminder calls before a urodynamics test helps women with pelvic floor disorders feel more prepared and less anxious, and whether it makes the procedure go more smoothly.

  Recruiting Ohio State University · Columbus, Ohio · NCT07692789

• Vaginal Vault Support at Hysterectomy

  This trial tests a new double-ligament vault suspension during hysterectomy to help prevent vaginal apex prolapse in women undergoing the procedure.

  Recruiting Assiut University · Asyut · NCT07517965

• Centered Surgery: Preoperative Counseling to Improve Patient Satisfaction

  This study will test whether virtual group counseling sessions (shared medical appointments) help adults having pelvic organ prolapse surgery feel more satisfied and better prepared compared with standard individual phone calls.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07471464

• Pelvic floor muscle training with and without hypopressive exercises for women with pelvic organ prolapse

  This will test whether adding hypopressive exercises to pelvic floor muscle training helps women aged 45–65 with stage I–II pelvic organ prolapse improve pelvic floor strength, reduce pain during sex, and feel better overall.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07440875

• Wrist activity tracking to guide early recovery after pelvic organ prolapse surgery

  This study will try giving women having pelvic organ prolapse surgery either usual postoperative advice or a guided early-exercise plan while tracking activity with a wrist accelerometer to see which group reaches "mostly recovered" sooner.

  Recruiting at 6 sites NICHD Pelvic Floor Disorders Network · San Diego, California and 6 other locations · NCT07218016

• Mesh-free sacrocolpopexy using the VNOTES (transvaginal endoscopic) approach for pelvic organ prolapse

  This trial will try mesh-free sacrocolpopexy using the VNOTES transvaginal endoscopic technique in women with stage II or higher pelvic organ prolapse to see if it improves pelvic support, symptoms, and sexual function over six months.

  Recruiting at 2 sites Gaziosmanpasa Research and Education Hospital · Istanbul and 1 other locations · NCT07114029

• Pelvic floor muscle training for first-time pregnant women

  This project will test whether a home-based, app-accessible pelvic floor exercise program helps first-time pregnant women reduce pelvic floor problems during pregnancy and after birth.

  Recruiting University of Southern Denmark · Aabenraa, Southern Denmark · NCT07104292

• V-NOTES versus Laparoscopic Mesh-Free Sacrocolpopexy for Pelvic Organ Prolapse

  This study will test whether V-NOTES mesh-free sacrocolpopexy works as well as or better than laparoscopic mesh-free sacrocolpopexy for women with apical and anterior pelvic organ prolapse.

  Recruiting Gaziosmanpasa Research and Education Hospital · Istanbul · NCT07082023

• Best timing for a midurethral sling during robotic pelvic organ prolapse repair

  This trial will test whether placing a midurethral sling before or after robotic sacrocolpopexy works better for women with stress urinary incontinence and pelvic organ prolapse.

  Recruiting at 2 sites University of Alabama at Birmingham · Birmingham, Alabama and 1 other locations · NCT07008898

• Rehabilitation for female pelvic floor dysfunction

  This study is testing different rehabilitation treatments for pelvic floor issues in Chinese women to see which ones work best for those with postpartum weakness and mild to moderate pelvic organ prolapse.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06461234

• Long-term evaluation of transvaginal mesh for pelvic organ prolapse

  This study follows women who had surgery for pelvic organ prolapse to see how well the treatments work and if there are any long-term problems up to 10 years later.

  Recruiting at 11 sites Peking Union Medical College Hospital · Foshan, Guangdong and 10 other locations · NCT05938881

• Registry for patients undergoing ventral mesh rectopexy for pelvic organ prolapse

  This study is collecting information from patients with pelvic organ prolapse who are having a specific type of surgery to see how well it works and what problems might come up later.

  Recruiting at 4 sites University Hospital, Antwerp · Brussels and 4 other locations · NCT05918367

• Home-based pelvic muscle training for pelvic floor disorders

  This study tests if using home-based pelvic muscle training devices can help people with stress urinary incontinence and pelvic organ prolapse just as well as traditional in-clinic training.

  Recruiting Taipei Veterans General Hospital, Taiwan · Taipei · NCT05778552

• Evaluating the safety and effectiveness of synthetic mesh surgery for pelvic organ prolapse

  This study is testing how safe and effective synthetic mesh surgery is for women with severe pelvic organ prolapse to see how well it works and what problems it might cause.

  Recruiting Mackay Medical College · New Taipei City · NCT05682989

• Comparing two surgical methods for pelvic organ prolapse repair

  This study is testing two different surgical methods to see which one works better for women over 50 with pelvic organ prolapse.

  Recruiting Charles University, Czech Republic · Hradec Králové and 7 other locations · NCT05602246

• Comparing two surgical methods for pelvic organ prolapse treatment

  This study is testing two different surgical methods to see which one works better and is safer for women with pelvic organ prolapse who need surgery.

  Recruiting National Cheng-Kung University Hospital · Tainan · NCT05586984

• Evaluating the long-term effects of Splentis for treating pelvic organ prolapse

  This study is testing how well the Splentis system works for treating uterine prolapse in women over five years, looking at both how they feel and any side effects they might have.

  Recruiting at 6 sites Promedon · Chemnitz and 6 other locations · NCT05042453

• Registry to evaluate pelvic mesh products for urinary incontinence and prolapse

  This study is testing how well certain surgical mesh products work for women having surgery for urinary incontinence and pelvic organ prolapse, while also looking at their safety and any complications after the surgery.

  Recruiting at 7 sites Ethicon, Inc. · New Haven, Connecticut and 9 other locations · NCT04829175

• Evaluating quality of life after treatments for pelvic organ prolapse

  This study is trying to see how different treatments for pelvic organ prolapse affect the quality of life and incontinence in patients over time.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT04110821

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Matrix Regenerative Nanotech to Slow Pelvic Organ Prolapse in Adults

  A new nanoparticle-based treatment aims to slow pelvic organ prolapse in adults by reconnecting and strengthening elastic tissue to improve quality of life.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11399996

• Identifying early warning signs of pelvic organ prolapse in young women

  This NIH grant aims to find early markers that signal risk of pelvic organ prolapse so we can prevent severe disease.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11384896

• New non-surgical option for treating pelvic organ prolapse

  This study is testing a new, easy-to-use pessary for women over 50 with pelvic organ prolapse, designed to be more comfortable and simpler to insert and remove on their own.

  NIH research Reia, LLC · Lyme, United States · NIH-11084311

• Creating a new type of graft to repair pelvic organ prolapse

  This study is working on a new type of graft to help fix pelvic organ prolapse, aiming to create a safe and effective solution that mimics healthy vaginal tissue, so patients can have better outcomes and fewer complications.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10889142

• Developing a new adhesive to prevent pelvic organ prolapse in women

  This study is working on a new, eco-friendly glue that can help women with early signs of vaginal wall detachment, which can lead to pelvic organ prolapse, by safely reattaching the vaginal wall to the pelvic muscles, aiming to prevent the need for surgery.

  NIH research University of Texas Arlington · Arlington, United States · NIH-10559652

Related topics

Quick answers

How many Pelvic Organ Prolapse clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (5 trials), Taiwan (3 trials), Turkey (Türkiye) (2 trials), China (2 trials), Denmark (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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