Condition

Pelvic Organ Prolapse (POP) clinical trials and research

• 12Clinical trials
• 10Countries

Newest Pelvic Organ Prolapse (POP) clinical trials

All recruiting trials (12)

• Risk predictor for new urinary incontinence after prolapse surgery

  This study tests a model to predict which women might develop new stress urinary incontinence after pelvic organ prolapse repair.

  Recruiting Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07601282

• Comparing the Manchester procedure versus vaginal hysterectomy for uterine prolapse

  This study tests whether the Manchester procedure or vaginal hysterectomy works better for women with symptomatic uterine prolapse over a two-year follow-up.

  Recruiting at 6 sites Tampere University Hospital · Helsinki and 5 other locations · NCT07566949

• Poly-L-lactic acid injections for vulvovaginal tissue regeneration

  This trial will try injections of poly-L-lactic acid (PLLA) versus placebo to see if they strengthen vaginal tissue and reduce bulge symptoms and sexual problems in women with stage II anterior vaginal wall prolapse (cystocele).

  Recruiting Duke University · Durham, North Carolina · NCT07544667

• Pelvic floor mesh used in laparoscopic sacrocolpopexy to repair pelvic organ prolapse

  This study tests the ProGYNious mesh to see if it safely and effectively repairs pelvic organ prolapse in adults undergoing laparoscopic surgery.

  Recruiting A.M.I. Agency for Medical Innovations GmbH · Wiener Neustadt, Lower Austria and 3 other locations · NCT07497321

• Paracervical block for pain control after vNOTES uterosacral ligament suspension

  This will test whether a paracervical injection of bupivacaine reduces early postoperative pain in women having vNOTES uterosacral ligament suspension for pelvic organ prolapse.

  Recruiting Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Istanbul, Istanbul · NCT07440576

• Postpartum pelvic floor recovery and early rehabilitation after vaginal birth

  This project tests whether early, individualized pelvic floor muscle training starting 2–3 weeks after a vaginal birth helps people with postpartum pelvic floor symptoms recover better than usual care.

  Recruiting at 2 sites Vastra Gotaland Region · Gothenburg and 1 other locations · NCT07430865

• Removing fallopian tubes and ovaries during vaginal hysterectomy: energy-sealing device versus standard technique

  This trial tests whether using a LigaSure energy-sealing device to remove the fallopian tubes and ovaries during vaginal hysterectomy is safer, faster, or causes less blood loss and pain than the standard clamping, cutting, and suturing method for women with pelvic organ prolapse.

  Recruiting Wolfson Medical Center · Holon · NCT07379411

• Vaginal versus robotic-assisted abdominal mesh repair for apical prolapse

  This study will test whether vaginal mesh repair works as well and is as safe as robotic-assisted abdominal mesh repair for women with stage II or higher apical pelvic organ prolapse.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07359755

• Wrist activity tracking to guide early recovery after pelvic organ prolapse surgery

  This study will try giving women having pelvic organ prolapse surgery either usual postoperative advice or a guided early-exercise plan while tracking activity with a wrist accelerometer to see which group reaches "mostly recovered" sooner.

  Recruiting at 6 sites NICHD Pelvic Floor Disorders Network · San Diego, California and 6 other locations · NCT07218016

• LatGYNious pelvic mesh for treating pelvic organ prolapse

  This study will try the LatGYNious preformed mesh during laparoscopic lateral suspension surgery to see if it improves prolapse symptoms in women who need surgical repair.

  Recruiting at 2 sites A.M.I. Agency for Medical Innovations GmbH · Sankt Johann in Tirol, Tyrol and 4 other locations · NCT07066761

• Vaginal estrogen after pelvic organ prolapse surgery

  This pilot trial compares no estrogen, twice-weekly estrogen, and daily estrogen given after pelvic organ prolapse repair to see which approach is feasible and acceptable.

  Recruiting Phase 3 Queen's University · St. John's, Newfoundland and Labrador and 1 other locations · NCT07030426

• Personalizable pessary for pelvic organ prolapse

  A new, custom-fit pessary made with 3D printing will be tested to see if it works as well as standard pessaries for women with pelvic organ prolapse.

  Recruiting University of Alberta · Edmonton, Alberta · NCT06954701

Related topics

Quick answers

How many Pelvic Organ Prolapse (POP) clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (2 trials), Canada (2 trials), Austria (2 trials), Germany (2 trials), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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