V-NOTES versus Laparoscopic Mesh-Free Sacrocolpopexy for Pelvic Organ Prolapse

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, comparative surgical study comparing two minimally invasive mesh-free techniques for apical and anterior pelvic organ prolapse repair: Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and conventional laparoscopy. Patients will be assigned to one of the two operative approaches and perioperative metrics such as operative time, blood loss, hospital stay, and pain scores will be collected. The study will track intraoperative and postoperative complications, anatomical success by POP‑Q, functional outcomes, and patient satisfaction over follow-up. The goal is to determine whether the V-NOTES route provides comparable or superior outcomes to laparoscopic mesh-free sacrocolpopexy without using synthetic mesh.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients who applied to Gaziosmanpaşa Education and Research Hospital, Gynecology and Obstetrics Clinic, who underwent surgery due to symptomatic pelvic organ prolapse with apical and anterior POP Q stage 2 and above, Being over 18 years old Patients who underwent surgery by experienced surgeons

Exclusion Criteria:

* Having previously received KT and/or RT due to any malignancy Having previously undergone surgery due to proplasus Patients with severe cardiovascular or respiratory disease

Where it's running

• Gaziosmanpasa Training and Research Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: havva betül bacak, md — Gaziosmanpaşa Training and Research Hospital
• Study coordinator: ecenur çelikoğlu, md
• Email: ecenurcelikoglu14@gmail.com
• Phone: +90 538 54 92 848

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.