Mesh-free sacrocolpopexy using the VNOTES (transvaginal endoscopic) approach for pelvic organ prolapse

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective clinical study at Gaziosmanpaşa Training and Research Hospital enrolling women with apical and/or anterior POP-Q stage II or higher who are candidates for sacrocolpopexy. Participants will undergo mesh-free sacrocolpopexy performed transvaginally with endoscopic (VNOTES) guidance and all surgeries will be done by experienced surgeons. Anatomical and functional outcomes will be measured before surgery and at six months after surgery using POP-Q, PFDI-20, and PISQ-12, and intraoperative data (operative time, blood loss, complications, length of stay) will be recorded. The primary endpoint is anatomical success by POP-Q change, with secondary endpoints including symptom improvement, sexual function, recurrence, and patient satisfaction.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients who applied to Gaziosmanpasa Education and Research Hospital, Gynecology and Obstetrics Clinic, have apical and anterior POP Q stage 2 and above, and have undergone surgery due to symptomatic pelvic organ prolapse, Patients who are over the age of 18 and who are citizens of the Republic of Turkey, and who have undergone surgery by experienced surgeons will be included in the study.

Exclusion Criteria:

Having previously received KT and/or RT due to any malignancy Having previously undergone surgery due to prolapse Patients with severe cardiovascular or respiratory diseases will not be included in the study.

Where it's running

• Gaziosmanpaşa Training and Research Hospital
  Istanbul, Turkey (Türkiye) Recruiting
• Gaziosmanpaşa Training and Research Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: havva betül bacak, md — Gaziosmanpasa Training and Research Hospital
• Study coordinator: yağmur acıyiyen, md
• Email: yagmuraciyiyen95@gmail.com
• Phone: +905425669593

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.