Creating a new type of graft to repair pelvic organ prolapse
Development of a Novel Bioinspired Pelvic Organ Prolapse Repair Graft
This study is working on a new type of graft to help fix pelvic organ prolapse, aiming to create a safe and effective solution that mimics healthy vaginal tissue, so patients can have better outcomes and fewer complications.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10889142 on NIH RePORTER |
What this research studies
This research focuses on developing a novel graft specifically designed to repair pelvic organ prolapse (POP), a condition that often leads to complications and reoperations. The approach involves studying the natural structure and function of healthy vaginal tissue to create a synthetic graft that mimics these properties. By utilizing advanced 3D printing techniques, the researchers aim to produce a biocompatible graft that supports cell adhesion and reduces the risk of failure. The project will also investigate how the mechanical and biochemical properties of the graft influence cellular behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from pelvic organ prolapse who are seeking surgical repair options.
Not a fit: Patients who do not have pelvic organ prolapse or those who are not candidates for surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and durable treatments for pelvic organ prolapse, significantly improving patient outcomes.
How similar studies have performed: While there have been advancements in graft development for various surgical applications, this specific approach using bioinspired materials for pelvic organ prolapse repair is relatively novel.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Egnot, Morgan Lee — University of Pittsburgh at Pittsburgh
- Study coordinator: Egnot, Morgan Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.