Comparing two surgical methods for pelvic organ prolapse treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the therapeutic efficacy and safety of laparoscopic uterine lateral suspension with transvaginal sacrospinous ligament fixation for treating pelvic organ prolapse. It focuses on patients who are dissatisfied with conservative treatments or have severe symptoms requiring surgical intervention. The trial aims to evaluate long-term outcomes, including safety and adverse events associated with both surgical approaches. By analyzing these methods, the study seeks to provide insights into the best practices for uterus-preserving surgeries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* older than 21 years old.
* uterine prolapse stage 2 at least, defined by C point distal to -1cm by POP-Q system.
* patients willing to receive a uterine-preserving surgery for pelvic organ prolapse, and is suitable for anesthesia after evaluation.
* patients who had or had not received conservative treatments for pelvic organ prolapse.
* patients able and willing to finish the questionnaire evaluation.

Exclusion Criteria:

* patient who had received a previous hysterectomy, or is planning on concomitant hysterectomy in the surgery for pelvic organ prolapse.
* patient who had received a previous surgery for pelvic organ prolapse.
* patient with history of adverse events following a synthetic mesh.
* patients with chronic or acute pelvic pain.
* patients who had received abdominal or pelvic irradiation.
* patients who cannot receive either surgery due to comorbidity.
* patients pregnant or with future plan of pregnancy.
* patients with vaginal length less than 5cm.

Where it's running

• National Cheng Kung University Hospital
  Tainan, Taiwan Recruiting

Study contacts

• Study coordinator: Yu Fang Huang, MD
• Email: yufangh@ncku.edu.tw
• Phone: 886-6-2353535

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.