Condition

Osteogenesis Imperfecta clinical trials and research

• 8Clinical trials
• 6Countries

Newest Osteogenesis Imperfecta clinical trials

All recruiting trials (8)

• Using REMS ultrasound to check bone density in children and teens with conditions that lower bone strength

  This project will test whether REMS, a radiation-free ultrasound method, can measure bone mineral density in children and adolescents aged 5–18 who have conditions that weaken their bones.

  Recruiting Meyer Children's Hospital IRCCS · Florence, Tuscany · NCT07412782

• Pediatric safety follow-up after romosozumab treatment for osteogenesis imperfecta

  This follow-up tests the safety of romosozumab in children and adolescents with osteogenesis imperfecta who previously received romosozumab in an earlier trial.

  Recruiting at 4 sites Phase 3 Amgen · Indianapolis, Indiana and 3 other locations · NCT07366086

• Heart structure and function in children and adults with Osteogenesis Imperfecta

  This project will follow children and adults with Osteogenesis Imperfecta to see how their heart structure and function change over a five-year period.

  Recruiting Istituto Ortopedico Rizzoli · Bologna, Emilia-Romagna · NCT07287241

• Adapted physical activity program for children and teenagers with Osteogenesis Imperfecta

  This study tests if a special 6-month exercise program can help children and teenagers with Osteogenesis Imperfecta improve their energy levels and overall fitness.

  Recruiting University Hospital, Toulouse · Montpellier and 1 other locations · NCT05927389

• Evaluating hearing and balance in children and young adults with Osteogenesis Imperfecta

  This study is testing how Osteogenesis Imperfecta affects hearing and balance in kids and young adults aged 12 to 20 to better understand the condition's impact.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT05419960

• Effects of bisphosphonates on hearing loss in osteogenesis imperfecta

  This study is testing if a medication called bisphosphonates can help adults with Osteogenesis Imperfecta type I who have hearing loss.

  Recruiting Phase 4 Hospital for Special Surgery, New York · New York, New York · NCT04152551

• Registry for Osteogenesis Imperfecta

  This study is creating a registry to gather information from people with Osteogenesis Imperfecta to better understand the condition and improve how it's managed and treated.

  Recruiting Istituto Ortopedico Rizzoli · Bologna, Emilia-Romagna · NCT04115774

• Long-term follow-up of individuals with Osteogenesis Imperfecta

  This study is tracking 1,000 people with Osteogenesis Imperfecta over five years to see how the condition affects their bones, spine, and dental health, which will help improve future treatments.

  Recruiting at 12 sites Baylor College of Medicine · Phoenix, Arizona and 11 other locations · NCT02432625

Related topics

Quick answers

How many Osteogenesis Imperfecta clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), Italy (3 trials), France (2 trials), Canada (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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