Adapted physical activity program for children and teenagers with Osteogenesis Imperfecta

BONeMOVE : an Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Osteogenesis Imperfecta: an Interventional, Prospective, Regional, Bicentric Study.

Not applicable Interventional University Hospital, Toulouse · NCT05927389

This study tests if a special 6-month exercise program can help children and teenagers with Osteogenesis Imperfecta improve their energy levels and overall fitness.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages7 Years to 18 Years
SexAll
SponsorUniversity Hospital, Toulouse Academic / other
Locations2 sites (Montpellier and 1 other locations)
Trial IDNCT05927389 on ClinicalTrials.gov

What this trial studies

This research evaluates the impact of a 6-month adapted physical activity program on the endurance capacities of children and adolescents diagnosed with Osteogenesis Imperfecta. The study focuses on improving maximum oxygen consumption (VO2 peak) to address chronic fatigue and decreased physical endurance commonly experienced by these patients. By engaging in tailored physical activities, the program aims to enhance muscle function and overall quality of life for participants. The study is conducted at University Hospital in Toulouse and CHU Montpellier.

Who should consider this trial

Good fit: Ideal candidates for this study are children and adolescents diagnosed with Osteogenesis Imperfecta who can walk and have parental consent.

Not a fit: Patients who are non-walking, pregnant, breastfeeding, or participating in other interventional research may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve the physical endurance and quality of life for children and teenagers with Osteogenesis Imperfecta.

How similar studies have performed: Previous studies have shown that physical activity can improve muscle function and quality of life in patients with chronic diseases, suggesting potential success for this approach in Osteogenesis Imperfecta.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed Osteogenesis Imperfecta
* Informed and written consent signed by at least one of the two holders of parental authority
* Patient affiliated to a social security scheme or equivalent

Exclusion Criteria:

* Non-walking children (unable to perform the effort test)
* Pregnant or breastfeeding
* Participation in other interventional research

Where this trial is running

Montpellier and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteogenesis ImperfectaChildrenAdolescentsMaximum oxygen consumptionAdapted physical activityEffort rehabilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.