Condition
Osteogenesis Imperfecta (OI) clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Osteogenesis Imperfecta (OI) clinical trials that are recruiting, at sites in 10 countries (most in Italy (1), China (1), Argentina (1)). By phase: Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 10Countries
Newest Osteogenesis Imperfecta (OI) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Dose-finding study of AGA2115 in Chinese adults and adolescents with osteogenesis imperfecta | Phase 2 | Beijing, Beijing Municipality and 4 other locations | Recruiting | Apr 29, 2026 |
| Heart structure and function in children and adults with Osteogenesis Imperfecta | — | Bologna, Emilia-Romagna | Recruiting | Dec 17, 2025 |
| AGA2115 treatment for adults with osteogenesis imperfecta caused by COL1A1 or COL1A2 variants | Phase 2 | Phoenix, Arizona and 25 other locations | Recruiting | Jul 14, 2025 |
All recruiting trials (3)
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Dose-finding study of AGA2115 in Chinese adults and adolescents with osteogenesis imperfecta
This study tests three different dosing regimens of AGA2115 in Chinese adults and adolescents with Osteogenesis Imperfecta to see how safe it is and how well it works.
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Heart structure and function in children and adults with Osteogenesis Imperfecta
This project will follow children and adults with Osteogenesis Imperfecta to see how their heart structure and function change over a five-year period.
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AGA2115 treatment for adults with osteogenesis imperfecta caused by COL1A1 or COL1A2 variants
This will test whether the drug AGA2115 helps adults (18–75) with Type I, III, or IV osteogenesis imperfecta due to COL1A1 or COL1A2 genetic variants.
Related topics
Quick answers
How many Osteogenesis Imperfecta (OI) clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 10 countries. The most sites are in Italy (1 trial), China (1 trial), Argentina (1 trial), Australia (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.