Condition

Osteo Arthritis of the Knee clinical trials and research

• 8Clinical trials
• 7Countries

Newest Osteo Arthritis of the Knee clinical trials

All recruiting trials (8)

• Can robotic-assisted knee replacement with functional alignment improve outcomes vs. standard knee replacement?

  This trial tests whether using the VELYS robotic system during total knee replacement helps patients with knee osteoarthritis feel better and move more comfortably compared with conventional non-robotic surgery.

  Recruiting Golden Jubilee National Hospital · Glasgow, Scotland · NCT07551856

• BETY with intra-articular injections for knee osteoarthritis

  This will try whether adding BETY to intra-articular knee injections reduces pain and improves function in adults with stage 2 or 3 knee osteoarthritis.

  Recruiting Hacettepe University · Ankara, Samanpazarı · NCT07496203

• Home-based leg dexterity training for knee osteoarthritis

  This study will test whether an at-home leg dexterity device can reduce pain and improve function for people aged 40–85 with knee osteoarthritis compared with wobble-board exercises.

  Recruiting Steadman Philippon Research Institute · Vail, Colorado · NCT07397806

• Catheter embolization of small knee arteries to relieve osteoarthritis pain

  This study will try using a catheter procedure to block small arteries around the knee to reduce chronic pain in adults 40–80 with knee osteoarthritis or persistent pain after knee replacement who haven't found enough relief from standard treatments.

  Recruiting Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. · Ústí nad Labem · NCT07361198

• Adding sensory nerve blocks to local pain injections for total knee replacement

  This trial tests whether adding three sensory nerve blocks to standard local pain injections reduces pain and opioid use after primary unilateral total knee replacement.

  Recruiting Phase 4 Region Skane · Trelleborg · NCT07350252

• Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy for Older Adults with Knee Osteoarthritis

  This trial will test whether applying high-intensity pulsed electromagnetic fields to both the knee and quadriceps reduces pain and improves function more than applying it only to the knee in adults 60 and older with knee osteoarthritis.

  Recruiting Hospital Civil de Guadalajara · Guadalajara, Jalisco · NCT07198750

• Methotrexate for knee osteoarthritis with ultrasound-proven synovitis

  This randomized trial will try methotrexate versus placebo to see if it reduces pain and inflamed lining (synovitis) in people aged 40–70 with knee osteoarthritis confirmed by ultrasound.

  Recruiting Phase 2 Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Dhaka, Dhaka Division · NCT07161336

• Comparing two nerve-block combinations to reduce pain after total knee replacement

  This test compares whether adding a distal IPACK block or a popliteal plexus block to a femoral triangle block reduces pain after total knee replacement.

  Recruiting Karaman Training and Research Hospital · Karaman · NCT07130552

Related topics

Quick answers

How many Osteo Arthritis of the Knee clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Turkey (Türkiye) (2 trials), Czechia (1 trial), Bangladesh (1 trial), United States (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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