Condition

Nicotine Use Disorder clinical trials and research

• 9Clinical trials
• 3Countries

Newest Nicotine Use Disorder clinical trials

All recruiting trials (9)

• Temporal interference stimulation for nicotine vaping addiction

  This trial will test whether a non-invasive brain stimulation method called temporal interference can lower cravings and reduce vaping in adults who use nicotine.

  Recruiting at 2 sites Indiana University · Bloomington, Indiana and 1 other locations · NCT07210268

• Tobacco cessation program for community behavioral health sites in Chicago

  This project will test a community-informed smoking cessation program to help adults who smoke and receive services at behavioral health organizations in Chicago.

  Recruiting University of Chicago · Chicago, Illinois · NCT06837220

• tDCS plus varenicline to help people quit smoking

  This will test if adding noninvasive tDCS brain stimulation to varenicline helps adults who smoke at least 8 cigarettes a day quit and stay smoke-free.

  Recruiting Phase 4 Centre for Addiction and Mental Health · Toronto, Ontario · NCT06798324

• Optimizing TMS Pulse Protocols for Reward Processing in Smokers

  This study is trying out different brain stimulation techniques to see if they can help smokers manage their cravings and make better decisions.

  Recruiting Rutgers, The State University of New Jersey · Newark, New Jersey · NCT06695884

• Real-time telecounselling for quitting nicotine addiction

  This study is testing whether real-time telecounseling can help people quit smoking by providing them with weekly therapy sessions.

  Recruiting Overcome · Leicester, Midlands · NCT06544057

• How cooling ingredients and menthol change the feel of nicotine e-liquids for adult vapers

  This project will test whether cooling chemicals (WS-3, WS-23) and menthol make nicotine e-liquids more appealing or habit-forming for adults who use e-cigarettes.

  Recruiting Yale University · New Haven, Connecticut · NCT05932745

• Identifying the best brain target for TMS to help smokers

  This study is testing if a specific brain stimulation technique can help smokers by improving their decision-making and reducing cravings.

  Recruiting Rutgers, The State University of New Jersey · Newark, New Jersey · NCT05766254

• Impact of Menstrual Cycle Phase on Smoking Cessation

  This study tests if starting smoking cessation treatment during certain phases of the menstrual cycle helps women quit smoking more successfully.

  Recruiting Phase 4 Centre for Addiction and Mental Health · Toronto, Ontario · NCT05515354

• Using incentives to reduce alcohol and smoking in treatment-seeking individuals

  This study is testing if a combination of rewards and a smoking cessation drug can help adults with alcohol use disorder cut down on drinking and smoking while they are getting treatment.

  Recruiting Phase 2 Washington State University · Spokane, Washington · NCT05181891

Related topics

Quick answers

How many Nicotine Use Disorder clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (6 trials), Canada (2 trials), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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