Using incentives to reduce alcohol and smoking in treatment-seeking individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial aims to evaluate the effectiveness of contingency management, combined with varenicline, in reducing alcohol consumption and cigarette smoking among adults with alcohol use disorder who are seeking treatment. Participants will receive either the contingency management intervention or a non-contingent control, alongside manualized counseling through module videos. The study focuses on individuals who have initiated pharmacotherapy for smoking cessation and have a history of heavy drinking. The goal is to determine if these behavioral strategies can significantly improve treatment outcomes for co-addicted individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 4 or more standard drinks on the same occasion for women (5 or more standard drinks on the same occasion for men) on at least 4 occasions in the prior 30 days
2. Seeking AUD treatment
3. Seeking smoking cessation treatment
4. Aged 18+ years
5. DSM-5 diagnosis of AUD
6. Currently smoking daily according to PhenX Smoking Status (100 or more lifetime cigarettes plus current daily smoking)
7. Ability to read and speak English
8. Ability to provide written informed consent
9. Breath alcohol of 0.00 during informed consent
10. Provision of at least 1 EtG-positive urine test at any time during the induction period and at least one COT-positive urine test at any time during the induction period; and
11. Attended at least 4 of 6 possible visits during the induction period.

Exclusion Criteria:

1. Significant risk of dangerous alcohol withdrawal, defined as a history of alcohol detoxification or seizure in the last 12 months and expression of concern by the participant about dangerous withdrawal
2. Currently receiving any pharmacotherapy for alcohol
3. Currently receiving any pharmacotherapy for smoking
4. No suicide attempt in the last 20 years and
5. Any other medical (discernable by initial blood tests) or psychiatric condition that Drs. Layton or Rodin determine would compromise safe participation.

Where it's running

• Washington State University
  Spokane, Washington, United States Recruiting

Study contacts

• Principal investigator: Sterling M McPherson, PhD — Washington State University
• Study coordinator: Research Coordinator
• Email: wsu.appl@wsu.edu
• Phone: 509-638-2376

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.