Condition

Neoplasm clinical trials and research

• 11Clinical trials
• 13NIH research projects
• 9Countries

Newest Neoplasm clinical trials

All recruiting trials (11)

• 4D MRI parameters linked to cardiovascular and cancer disease outcomes

  This study tests whether 4D MRI measurements can predict how cardiovascular diseases and cancer will progress in adults undergoing routine cardiac MRI at a single Korean hospital.

  Recruiting Ulsan University Hospital · Ulsan, Ulsan · NCT07678606

• Intratumoral injection of mechanically reprogrammed macrophage-derived exosomes for advanced solid tumors

  This trial will test whether injecting mechanically reprogrammed macrophage-derived exosomes directly into tumors is safe and tolerable in adults 18–65 with advanced solid tumors who have no standard treatment options.

  Recruiting Phase 1 West China Hospital · Chengdu, Sichuan · NCT07563972

• EMDR group program with optional individual EMDR for people with cancer

  This project will try EMDR group therapy plus optional individual EMDR to reduce PTSD symptoms and psychological distress in people diagnosed with cancer.

  Recruiting Università Cattolica di Milano · Milan · NCT07447089

• KLN-1010 gene therapy for relapsed or refractory multiple myeloma

  This Phase 1 trial will try KLN-1010, an in vivo CAR‑T gene therapy, to see if it is safe and can be given at a tolerable dose for people with relapsed or refractory multiple myeloma who have had at least three prior therapies.

  Recruiting at 11 sites Phase 1 Kelonia Therapeutics, Inc. · Duarte, California and 10 other locations · NCT07075185

• Creating a network for precision oncology in central-southern Italy

  This study is trying to create a network of labs in central-southern Italy to better understand cancer by improving testing methods and sharing information about tumors to help personalize treatment for patients.

  Recruiting National Cancer Institute, Naples · Naples · NCT06894823

• Adaptive care for Chinese cancer survivors with insomnia

  This study is testing whether a web-based therapy for insomnia or an online exercise program can help Chinese cancer survivors sleep better, and if those who still have trouble can benefit from more intensive face-to-face support.

  Recruiting The University of Hong Kong · Hong Kong · NCT06813235

• Positive activities for Asian American cancer patients and their caregivers

  This study is testing a new program that encourages positive activities for Asian American cancer patients and their caregivers to see if it helps improve their mental well-being.

  Recruiting Fox Chase Cancer Center · Philadelphia, Pennsylvania · NCT06782581

• Assessing COM503 for advanced solid tumors

  This study is testing a new treatment called COM503, alone and with another drug, to see how safe it is for people with advanced solid tumors who haven't responded to other therapies.

  Recruiting at 11 sites Phase 1 Compugen Ltd · New Haven, Connecticut and 10 other locations · NCT06759649

• Radiation before mastectomy with immediate breast reconstruction

  This trial tests whether giving radiation before mastectomy combined with immediate breast reconstruction improves cosmetic results and quality of life for women who need mastectomy and post‑mastectomy radiation.

  Recruiting at 4 sites Cancer Research Antwerp · Edegem, Antwerpen and 5 other locations · NCT06739655

• Helping employees with cancer return to work by supporting their employers

  This study tests a new program that helps employers support employees with cancer in returning to work successfully.

  Recruiting at 5 sites Phase 2/3 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Arnhem and 4 other locations · NCT06672887

• Access to targeted cancer therapies based on tumor genetics

  This study is testing if matching advanced cancer patients with targeted treatments based on their tumor genetics can improve their outcomes and make it easier for them to access these therapies.

  Recruiting at 34 sites Phase 2 The Netherlands Cancer Institute · Alkmaar and 35 other locations · NCT02925234

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Complement and clotting in JAK2V617F myeloproliferative neoplasms

  A short, patient-friendly study will look at how a specific mutation in blood cells may trigger the body’s complement system to cause clots in people with myeloproliferative neoplasms.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11437026

• Endothelial contribution to blood-clotting in myeloproliferative neoplasms

  This project explores how the lining of blood vessels may drive dangerous clots in people with myeloproliferative neoplasms (MPNs).

  NIH research University of Minnesota · Minneapolis, United States · NIH-11392884

• Hypoxia-inducible factors and neutrophil diversity in blood clotting in myeloproliferative neoplasms

  A physician-scientist is training over five years to uncover how low-oxygen signals and diverse neutrophils drive dangerous clots in people with myeloproliferative neoplasms, with the goal of finding new treatment targets.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11380793

• Inherited genetic risks shaping myeloid cancer initiation

  A research project at Boston Children’s Hospital is exploring how inherited genetic differences may push blood stem cells toward the start of myeloproliferative neoplasms, with potential implications for earlier detection and prevention.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11364935

• Understanding why some myeloproliferative neoplasm patients resist interferon therapy

  Researchers are studying why interferon-alpha works for some blood cancer patients but not others, by looking closely at stem cells from CALR-mutated myeloproliferative neoplasms.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11357543

• Genetic and epigenetic factors shaping response in advanced myeloproliferative neoplasms

  This grant looks at how genetic and epigenetic differences influence how patients with advanced myeloproliferative neoplasms respond to therapies.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11352898

• Understanding why some patients with blood cancers don't respond to interferon-alpha treatment

  This study is looking at how certain blood cancer stem cells with CALR mutations react to a treatment called interferon-alpha, to help understand why some patients improve in their blood counts but not in tumor size, which could lead to better treatments for people with blood cancers.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11180710

• Understanding inherited risks for blood cancers called myeloproliferative neoplasms

  This work explores how inherited genetic differences can make some people more likely to develop certain blood cancers, called myeloproliferative neoplasms.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11114017

• Understanding why some patients with blood cancers don't respond to interferon-alpha treatment

  This study is looking at how a specific type of blood cancer stem cell, especially those with CALR mutations, reacts to a treatment called interferon-alpha, to help understand why some patients benefit from the therapy even if their tumors don't shrink, with the goal of finding better treatment options for people with

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11087672

• Understanding blood clotting mechanisms in certain blood cancers

  This study is looking into how blood clots form in people with myeloproliferative neoplasms (a type of blood cancer) to find new ways to help prevent serious complications, and it’s designed for patients who want to learn more about their condition and potential treatments.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10895397

• Understanding how blood vessel cells contribute to blood clots in certain blood cancers

  This study is looking at how certain cells in your blood vessels might contribute to blood clots in people with myeloproliferative neoplasms (MPNs), especially those with a specific mutation, and it aims to understand how current medications can help, with the possibility of you providing blood samples to assist in thi

  NIH research University of Minnesota · Minneapolis, United States · NIH-10895325

• Understanding inherited genetic factors that lead to blood cancers.

  This study is looking at how inherited genes might play a role in the development of blood cancers called myeloproliferative neoplasms, using mice to understand how these genes affect blood stem cells, which could help patients learn more about their own genetic risks and ways to prevent these conditions.

  NIH research Boston Children's Hospital · Boston, United States · NIH-10867306

• Investigating a rare and aggressive blood cancer called BPDCN

  This study is looking at a rare and serious blood cancer called BPDCN to find out how certain genetic changes affect the disease, with the hope of discovering new treatments that could help patients like you.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-10855766

Related topics

Quick answers

How many Neoplasm clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (3 trials), Netherlands (2 trials), Italy (2 trials), Australia (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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