Understanding blood clotting mechanisms in certain blood cancers
Hypoxia-Inducible Factors and Neutrophil Heterogeneity in Myeloproliferative Neoplasm-Associated Venous Thrombosis
This study is looking into how blood clots form in people with myeloproliferative neoplasms (a type of blood cancer) to find new ways to help prevent serious complications, and it’s designed for patients who want to learn more about their condition and potential treatments.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10895397 on NIH RePORTER |
What this research studies
This research focuses on exploring the mechanisms behind blood clotting in patients with myeloproliferative neoplasms (MPN), a type of blood cancer. The project aims to identify specific factors that contribute to thrombosis, which is a serious complication in these patients. By developing a deeper understanding of how blood cells behave in MPN, the research seeks to uncover new treatment targets that could improve patient care. The approach includes a combination of coursework, seminars, and hands-on research under the guidance of experienced mentors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with myeloproliferative neoplasms, particularly those experiencing complications related to blood clotting.
Not a fit: Patients with other types of blood disorders or those not diagnosed with myeloproliferative neoplasms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and better management of thrombotic events in patients with myeloproliferative neoplasms.
How similar studies have performed: Previous research has shown promising results in understanding thrombotic mechanisms in related conditions, indicating that this approach has potential for success.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Reeves, Brandi N — Univ of North Carolina Chapel Hill
- Study coordinator: Reeves, Brandi N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.