Condition

Multiple Sclerosis (MS) clinical trials and research

• 13Clinical trials
• 7Countries

Newest Multiple Sclerosis (MS) clinical trials

All recruiting trials (13)

• QH103 (universal CD19 CAR-γδT) cell injections for relapsed or treatment‑resistant antibody-driven neurological autoimmune diseases

  This Phase 1 test will see if QH103 (universal CD19 CAR-γδT) cell injections are safe and tolerated in adults with relapsed or treatment‑resistant antibody-mediated neurological diseases such as MS, NMOSD, AE, CIDP, or MG.

  Recruiting Phase 1 Tongji Hospital · Wuhan, Hubei · NCT07526493

• Can QSM MRI help tell MS from age-related brain changes in older adults

  This study tests whether an advanced MRI technique called QSM can better differentiate MS-related brain lesions from age-related or small vessel changes in people aged 50–70.

  Recruiting Oslo University Hospital · Oslo, Oslo · NCT07444047

• Escalation versus induction therapy for relapsing MS starting after age 50

  This project will test whether starting with stronger, highly effective treatments or beginning with moderate drugs and escalating later changes the risk of inflammatory relapses for people whose relapsing MS began after age 50.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07313462

• Impact of a Palliative Care Model on Patient Knowledge and Attitudes

  This study tests if a video about palliative care can help people with Multiple Sclerosis understand their treatment options better than just reading a pamphlet.

  Recruiting at 2 sites Hunter College of City University of New York · New York, New York and 1 other locations · NCT06860932

• Observational study on CNS inflammatory demyelinating diseases in the Chinese population

  This study is looking to understand how certain brain diseases, like Multiple Sclerosis, affect people in China and what factors might influence their progression and treatment.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06541626

• C-CAR168 treatment for autoimmune diseases not responding to standard therapy

  This study is testing a new treatment called C-CAR168 to see if it can help adults with autoimmune diseases that haven't improved with standard therapies.

  Recruiting Phase 1 RenJi Hospital · Shanghai, Shanghai Municipality · NCT06249438

• Exploring brain imaging to understand neurodegeneration in multiple sclerosis

  This study is testing how brain imaging can help us understand the brain changes in people with multiple sclerosis who have been living with the condition for a long time.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT05633875

• Evaluating a new imaging biomarker for neuroinflammation in neurodegenerative diseases

  This study is testing a new imaging tool to see if it can help us understand brain inflammation in people with neurodegenerative diseases like ALS, Alzheimer’s, multiple sclerosis, and Parkinson’s, as well as in healthy volunteers.

  Recruiting at 3 sites Phase 1/2 Ashvattha Therapeutics, Inc. · San Francisco, California and 2 other locations · NCT05395624

• Assessing the effects of Clemastine Fumarate on myelin repair in MS patients

  This study is testing if a medication called Clemastine Fumarate can help repair the protective covering of nerves in people with relapsing-remitting multiple sclerosis.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT05359653

• Imaging axonal damage and repair in multiple sclerosis

  This study is testing new MRI techniques to see how axons are damaged and repaired in people with multiple sclerosis over two years.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT05177523

• Observing pregnancy outcomes in women with multiple sclerosis

  This study looks at how pregnancy affects women with multiple sclerosis to see what happens to their health during this time.

  Recruiting Charite University, Berlin, Germany · Berlin · NCT05010902

• Detecting spinal cord lesions in multiple sclerosis using advanced MRI techniques

  This study is testing a new MRI technique to see if it can better detect spinal cord lesions in people with multiple sclerosis.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT04819737

• Metformin to activate neural progenitor cells in children and young adults with MS

  This trial will try giving metformin or placebo to children and young adults with MS to see if metformin helps the brain cells that repair myelin.

  Recruiting Phase 1/2 The Hospital for Sick Children · Toronto, Ontario · NCT04121468

Related topics

Quick answers

How many Multiple Sclerosis (MS) clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (3 trials), China (3 trials), France (2 trials), Switzerland (2 trials), Norway (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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