Observational study on CNS inflammatory demyelinating diseases in the Chinese population

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the pathogenesis and clinical prognosis of central nervous system idiopathic inflammatory demyelinating diseases (CNS IIDD) such as Multiple Sclerosis and Neuromyelitis Optica in the Chinese population. It will clarify clinical characteristics and prognostic factors of these diseases while analyzing the relationship between biomarkers and disease progression. Participants will receive standard diagnosis and treatment plans based on current guidelines, along with clinical evaluations and follow-ups from neuroimmunology specialists.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients aged 18-65 years with central nervous system idiopathic inflammatory demyelinating diseases (CNS IIDD);
2. The clinical syndrome of the attack meets one of the following: MS, NMOSD, MOGAD, ADEM, clinically isolated syndrome, demyelinating encephalopathy, demyelinating myelitis, or brainstem encephalitis (see below A-E);
3. Agree to participate in this study and sign the informed consent form.

Exclusion Criteria:

1. History of tumors or diagnosis of central nervous system tumors;
2. Infectious lesions of the central nervous system;
3. Hereditary, metabolic, toxic, vascular, or traumatic demyelinating diseases of the brain/spinal cord;
4. Non-compliance with treatment and follow-up.

Where it's running

• Sun Yat-sen Memorial Hospital
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Hongxuan Wang
• Email: wanghx8@mail.sysu.edu.cn
• Phone: 86+13824498978

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.