Condition
Multiple Sclerosis, Primary Progressive clinical trials and research
Research outlook What's coming for Multiple sclerosis: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 4 Multiple Sclerosis, Primary Progressive clinical trials that are recruiting, at sites in 2 countries (most in United States (3), Switzerland (1)). By phase: Phase 1 (1), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Multiple Sclerosis, Primary Progressive clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Observational study of patients with Multiple Sclerosis in Switzerland | — | Basel | Recruiting | Jul 29, 2024 |
| Anti-CD19 CAR-T for non-relapsing progressive multiple sclerosis | Phase 1 | Palo Alto, California | Recruiting | Nov 18, 2023 |
| Assessing the effects of Clemastine Fumarate on myelin repair in MS patients | Phase 1/2 | San Francisco, California | Recruiting | May 4, 2022 |
| Investigating risk factors for disability progression in Multiple Sclerosis | — | Los Angeles, California | Recruiting | Jan 24, 2022 |
All recruiting trials (4)
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Observational study of patients with Multiple Sclerosis in Switzerland
This study is trying to find out more about the early signs of Multiple Sclerosis and how it changes over time by looking at health data from patients in Switzerland.
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Anti-CD19 CAR-T for non-relapsing progressive multiple sclerosis
This Phase 1 trial will test whether a single infusion of KYV-101 (anti-CD19 CAR-T cells) is safe and can slow worsening in adults with non-relapsing progressive MS.
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Assessing the effects of Clemastine Fumarate on myelin repair in MS patients
This study is testing if a medication called Clemastine Fumarate can help repair the protective covering of nerves in people with relapsing-remitting multiple sclerosis.
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Investigating risk factors for disability progression in Multiple Sclerosis
This study is trying to find out what factors might make disability get worse in people with Multiple Sclerosis by looking at their medical history and MRI scans.
Related topics
Quick answers
How many Multiple Sclerosis, Primary Progressive clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (3 trials), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.