Condition

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease clinical trials and research

• 18Clinical trials
• 8Countries

Newest MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease clinical trials

All recruiting trials (18)

• See if a Mediterranean-style lifestyle program helps MASLD patients improve liver health

  This trial tests a Mediterranean diet plus personalized exercise plan in adults with MASLD to see if it improves liver and systemic markers.

  Recruiting Fundación Pública Andaluza para la gestión de la Investigación en Sevilla · Roma and 2 other locations · NCT07652151

• Exercise for an Aging Liver

  This study tests whether a supervised 12-week exercise program can reduce liver fat, inflammation, and fibrosis in adults with MASLD or at-risk MASH, comparing younger and older adults and different disease severities.

  Recruiting Consorcio Centro de Investigación Biomédica en Red (CIBER) · Madrid, Madrid · NCT07467512

• Spleen stiffness measurement to detect advanced liver fibrosis

  This study will test whether measuring spleen stiffness with a 100‑Hz probe can help detect advanced fibrosis and portal hypertension in adults with MASLD and compensated advanced chronic liver disease.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT07440511

• Extra virgin olive oil for liver and metabolic health in MASLD

  This trial will test whether taking extra virgin olive oil every day helps adults with MASLD and overweight reduce liver fat and improve blood sugar and cholesterol.

  Recruiting Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis · Castellana Grotte, Italy · NCT07412444

• Pulsendo for Type 2 Diabetes and fatty liver disease in adults

  This study tests the pulsENDO procedure in adults with type 2 diabetes who still have high blood sugar despite meds, to see if it helps their diabetes and fatty liver disease.

  Recruiting Chinese University of Hong Kong · Shatin · NCT07390422

• Time-restricted eating for fatty liver disease in obesity

  This study tests whether an 8-hour daily eating window can reduce liver fat in adults with obesity and MASLD, using coaching and a phone app alongside standard care.

  Recruiting Nantes University Hospital · Angers and 8 other locations · NCT07378072

• Gut microbiota–derived amino acid metabolites in MASLD/MASH

  This study tests whether gut microbiota–produced amino acid metabolites are linked to MASLD/MASH in adults by collecting stool, blood, and urine samples and analyzing dietary factors.

  Recruiting Hospices Civils de Lyon · Pierre-Bénite · NCT07313007

• Corazones Unidos: Heart health program for Mexican-origin adults

  This program tests whether a community health worker-led education and support program can increase heart disease risk awareness and encourage healthy lifestyle changes for Mexican-origin adults with MASLD in Southern Arizona.

  Recruiting University of Arizona · Tucson, Arizona · NCT07298213

• Ultrasound method to measure liver fat percentage

  This study will test whether a new ultrasound technique can accurately measure the percentage of fat in the liver for adults with or at risk for MASLD (formerly NAFLD) and for healthy volunteers.

  Recruiting ContextVision AB · Seattle, Washington · NCT07270601

• Daily probiotic mix for moderate MASLD in adults with overweight

  This will see if taking a daily Lactiplantibacillus plantarum probiotic mix for 6 months can reduce liver fat and stiffness in adults 18–75 with moderate MASLD and BMI 25–42.

  Recruiting Phase 2 AB Biotics, SA · Girona, Girona · NCT07193927

• Resmetirom treatment for adults with MASLD and HIV

  This study will test whether taking resmetirom daily for 24 weeks lowers liver fat in adults who have MASLD and well-controlled HIV on antiretroviral therapy.

  Recruiting at 5 sites Phase 2 Indiana University · Birmingham, Alabama and 9 other locations · NCT07143968

• Daily ketone ester drink to lower liver fat and improve metabolism

  This trial tests whether a daily ketone ester drink for 6 weeks can reduce liver fat and improve blood sugar control in 18–25-year-olds with MASLD who are overweight or have obesity.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT07097506

• Low‑methoxy pectin for inflammation, gut microbiome, and metabolic health in MASLD

  This tests whether taking daily low‑methoxy pectin for six weeks can reduce inflammation and improve gut bacteria and metabolic markers in adults with MASLD.

  Recruiting at 3 sites University of Nottingham · Nottingham, United Kingdom and 2 other locations · NCT07093346

• Fruit and vegetable vouchers to help children with MASLD and household food insecurity

  This program will try giving fruit and vegetable vouchers to families to see if children with MASLD who face food insecurity eat more produce and have better liver-related health.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07091539

• Household food insecurity and MASLD in children and adolescents

  This research will see if household food insecurity is linked to worse MASLD in children and adolescents who have elevated ALT and are overweight or obese.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07090083

• Using advanced ultrasound to evaluate liver disease in children

  This study is testing new ultrasound methods to see if they can help doctors better detect and monitor liver fat in children at risk for liver disease.

  Recruiting University of California, San Diego · La Jolla, California · NCT06706856

• Investigating heart problems in patients with fatty liver disease

  This study looks at how fatty liver disease might affect heart health in adults aged 18-65 by checking for heart problems like coronary artery disease and heart failure.

  Recruiting Post Graduate Institute of Medical Education and Research, Chandigarh · Chandigarh, Chandigarh · NCT06386094

• Non-invasive tool to predict fatty liver disease

  This study is testing a new, non-invasive tool to see if it can help identify fatty liver disease in healthy people and those already diagnosed with it.

  Recruiting Richmond Pharmacology Limited · London, London · NCT04873258

Related topics

Quick answers

How many MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (7 trials), Spain (3 trials), Italy (3 trials), United Kingdom (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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