Condition

Macular Holes clinical trials and research

• 7Clinical trials
• 9Countries

Newest Macular Holes clinical trials

All recruiting trials (7)

• Ten modern techniques for full-thickness macular hole repair compared

  We are testing ten different surgical approaches to fix full-thickness macular holes in adults to see which method closes the hole best and gives the best vision.

  Recruiting Kazakh Eye Research Institute · Almaty, Almaty · NCT07606404

• Comparing surgery times for UNITY® VCS and CONSTELLATION® Vision System

  This study will see if the UNITY® VCS or the CONSTELLATION® Vision System leads to shorter combined cataract and vitrectomy (phacovitrectomy) surgery times for adults planned for 25‑gauge procedures.

  Recruiting Alcon Research · Manchester · NCT07228091

• Decellularized amniotic membrane hydrogel vs inverted ILM flap for large macular holes

  This trial tests whether injecting decellularized human amniotic membrane hydrogel can close large macular holes as effectively as the inverted ILM flap technique after vitrectomy.

  Recruiting Walailak University · Nakhon Si Thammarat, Thasala · NCT06433284

• Repositioning the peeled inner limiting membrane to treat macular holes

  This study is testing a new surgery that moves a part of the eye to help close macular holes in older patients, instead of removing it like usual.

  Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai · NCT06359548

• Treatment of small macular holes using air

  This study tests whether using air instead of gas during surgery can help close small macular holes in the eyes for patients who have had them for less than a year.

  Recruiting at 6 sites Helse Stavanger HF · Thessaly, Thessaly and 6 other locations · NCT06211907

• Comparing face-down positioning durations after macular hole surgery

  This study is testing whether sitting face-down for 3 days or 7 days after macular hole surgery helps people heal better and see clearly.

  Recruiting St. Joseph's Healthcare Hamilton · Stoney Creek, Ontario · NCT06000111

• Using advanced imaging technology during eye surgery

  This study is testing a new imaging technology during eye surgery to see if it can help doctors perform better and improve outcomes for patients with retinal diseases.

  Recruiting Duke University · Durham, North Carolina · NCT03713268

Related topics

Quick answers

How many Macular Holes clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in Thailand (1 trial), United Kingdom (1 trial), China (1 trial), United States (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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