Repositioning the peeled inner limiting membrane to treat macular holes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates a novel surgical technique for treating macular holes by repositioning the peeled inner limiting membrane (ILM) instead of the conventional ILM peeling method. The approach aims to preserve the integrity of the internal retina while effectively closing the macular hole. Patients aged 50 to 80 years diagnosed with macular holes of a specific size will be recruited for this intervention. The study seeks to evaluate the effectiveness and safety of this new technique compared to traditional methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The patients are diagnosed as MH with a diameter ≤ 600 µm by optical coherence tomography.
2. Age ranges from 50 to 80 years.
3. Do not participate in other clinical studies.
4. Agree to sign an informed consent form with good compliance.

Exclusion Criteria:

1. Traumatic macular hole.
2. Combined with serious epiretinal membrane.
3. Combined with diabetic retinopathy, hypertensive retinopathy.
4. Combined with other ocular diseases, such as keratitis，uveitis，retinal vasculitis.
5. Spherical equivalent ≥ -6.0 diopters or axial length ≥ 26 mm.
6. History of intraocular surgery.
7. Presence of staphyloma.
8. Other ocular diseases that influence macular microstructure or visual function.

Where it's running

• Xinhua Hospital Affiliated to Shanghai Jiaotong University Medicine School
  Shanghai, China Recruiting

Study contacts

• Principal investigator: Tian Tian, MD，PhD — Xinhua Hospital, Shanghai Jiaotong University School of Medicine
• Study coordinator: Tian Tian, MD，PhD
• Email: tiantianoph@163.com
• Phone: +8615216695095

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Decellularized amniotic membrane hydrogel vs inverted ILM flap for large macular holes

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.