Comparing surgery times for UNITY® VCS and CONSTELLATION® Vision System
Official title: Surgical Procedure Efficiency Evaluation stuDy (SPEED): Combination Phaco-Vitrectomy Surgeries With UNITY VCS vs. Constellation in a Real-World Operating Room Setting
Run by Alcon Research · NCT07228091 · Data updated 2026-11-12
This study will see if the UNITY® VCS or the CONSTELLATION® Vision System leads to shorter combined cataract and vitrectomy (phacovitrectomy) surgery times for adults planned for 25‑gauge procedures.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 180 (estimated) |
| Sponsor | Alcon Research Industry-sponsored |
| Locations | 1 site (Manchester) |
| Status | Recruiting |
| Started | February 9, 2026 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | October 28, 2026 |
| Trial ID | NCT07228091 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who can consent and are scheduled for a planned combined phacoemulsification and 25‑gauge vitrectomy (phacovitrectomy) at a participating UK surgical site are ideal candidates.
✕Probably not a fit
Patients requiring emergency or unplanned phacovitrectomy, those who are pregnant, or those with prior phacovitrectomy in the planned operative eye are excluded and will not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-visit, real-world time-and-motion study conducted in the United Kingdom to compare surgical procedure times between the UNITY® VCS and the CONSTELLATION® Vision System during routine combined anterior–posterior segment (phacovitrectomy) operations. Eligible patients are adults scheduled for planned combined phacoemulsification and 25‑gauge vitrectomy at participating surgical sites, and procedures are observed and timed under normal operating conditions. Emergency or unplanned surgeries, pregnant patients, and eyes with prior phacovitrectomy are excluded. The study is sponsored by Alcon Research in collaboration with Manchester Royal Eye Hospital and focuses on workflow and efficiency rather than clinical outcomes.
Why it matters
Potential benefit: If successful, the results could help surgeons choose the system that shortens operating time and improves surgical efficiency, which may reduce anesthesia exposure and operating room costs.
How similar studies have gone: Device-comparison and time-and-motion studies have measured surgical workflow for vitrectomy systems before, but direct real-world comparisons between these two specific systems for combined phacovitrectomy are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Key Inclusion Criteria: * Able to understand and sign an informed consent form (ICF) that has been approved by an ethics committee. * Planned combined phacovitrectomy procedure at one of the selected surgical sites. * Planned combined phacovitrectomy procedure with 25-gauge (G) vitrectomy tools. Key Exclusion Criteria: * Unplanned/emergency phacovitrectomy. * Pregnant. * Past history of phacovitrectomy. cataract, vitrectomy in the planned operative eye. * Other protocol-defined exclusion criteria may apply.
Where it's running
-
Manchester Royal Eye Hospital
Manchester, United Kingdom Recruiting
Study contacts
- Study coordinator: Alcon Call Center
- Email: alcon.medinfo@alcon.com
- Phone: 1-888-451-3937
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using advanced imaging technology during eye surgery
This study is testing a new imaging technology during eye surgery to see if it can help doctors perform better and improve outcomes for patients with retinal diseases.
-
Rotational Stability of the Acunex Vario Toric
This study tests whether the Acunex Vario toric extended-depth-of-focus intraocular lens stays stable in rotation and effectively reduces astigmatism for people undergoing cataract surgery.
-
Anterior segment anatomy assessment with swept-source OCT in eye surgery patients
This study tests whether swept-source OCT can detail front-eye anatomy in patients undergoing anterior segment eye surgery.
-
MiLOOP-assisted cataract surgery for dense cataracts
In people with dense cataracts, this study tests whether using the miLOOP device during cataract surgery can protect corneal cells and reduce ultrasound energy, compared with standard surgery.
-
Visual adaptation and quality of life after different IOL implantation options
This study follows adults who have cataracts and receive bilateral multifocal or mixed IOLs to see how their vision and daily life improve over 6 months.
-
Biometry in Eyes with Silicon Oil After PPV
This study tests optical and ultrasound biometry in people with retinal detachment who are getting pars plana vitrectomy with silicone oil, to see how measurements compare before surgery and about a month after.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.