Condition

Knee Osteoarthritis (OA) clinical trials and research

• 10Clinical trials
• 13Countries

Newest Knee Osteoarthritis (OA) clinical trials

All recruiting trials (10)

• Platelet-rich plasma added to hyaluronic acid for knee osteoarthritis

  This study tests whether a single injection of hyaluronic acid plus autologous platelet-rich plasma helps reduce knee OA symptoms more than hyaluronic acid alone in adults with moderate knee OA.

  Recruiting Implai Sp z o.o · Warsaw, Masovian Voivodeship · NCT07785401

• Hyaluronic Acid Plus PRP Injection for Knee Osteoarthritis

  This study tests whether a single HA injection combined with a patient’s own PRP is better at easing knee OA pain than HA alone.

  Recruiting Implai Sp z o.o · Chełm, Lublin Voivodeship · NCT07784907

• Weekly NNC0487-0111 injections for weight loss and knee pain in adults with excess weight and knee osteoarthritis

  This will try weekly NNC0487-0111 injections versus placebo to see if adults with excess body weight and knee osteoarthritis can lose weight and have less knee pain.

  Recruiting at 73 sites Phase 3 Novo Nordisk A/S · Phoenix, Arizona and 81 other locations · NCT07481630

• Altered Joint Mechanics and Biological Response in Osteoarthritic Knees

  This study tests how braces or high tibial osteotomy (HTO) affect knee bone and cartilage in people with knee OA who are scheduled for corrective treatment.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT07481461

• Why walking causes different amounts of knee pain in people with osteoarthritis

  This project will see if differences in the brain, joint imaging, movement, and sensory responses explain why adults 45–80 with knee osteoarthritis have different levels of walking pain.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07308873

• Using anti-inflammatories and dextrose injections to treat knee osteoarthritis

  This study is testing whether combining anti-inflammatory medication with dextrose injections can help adults aged 45-75 with knee osteoarthritis feel less pain.

  Recruiting Phase 2 David Grant U.S. Air Force Medical Center · Travis AFB, California · NCT06911359

• Reducing knee pain with Genicular Artery Embolization

  This study is testing if a new procedure called Genicular Artery Embolization can help people with knee osteoarthritis pain who haven't found relief from other treatments.

  Recruiting Phase 2 University of Utah · Salt Lake City, Utah · NCT06859164

• Registry for Genicular Artery Embolization in Knee Osteoarthritis

  This study is trying to see if a new procedure called genicular artery embolization can help reduce knee pain in adults with osteoarthritis who aren't able to have surgery.

  Recruiting University of Chicago · Chicago, Illinois · NCT06781463

• Comparing core stabilization exercises and foot-ankle strengthening for knee osteoarthritis

  This study is testing whether core stabilization exercises or foot-ankle strengthening can help people with knee osteoarthritis feel less pain and improve their movement.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT06658249

• Spa therapy program for knee osteoarthritis

  This program tests whether an 18-day balneotherapy (spa) treatment helps people with knee osteoarthritis reduce pain, stiffness, and improve physical function.

  Recruiting CEN Biotech · Santenay, Burgundy · NCT06617975

Related topics

Quick answers

How many Knee Osteoarthritis (OA) clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (5 trials), Poland (3 trials), Pakistan (1 trial), Australia (1 trial), Bulgaria (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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