Comparing core stabilization exercises and foot-ankle strengthening for knee osteoarthritis
Official title: Comparative Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program on Pain, Physical Function and Quality of Life in Patients With Knee Osteoarthritis.
Run by Riphah International University · NCT06658249 · Data updated 2026-11-12
This study is testing whether core stabilization exercises or foot-ankle strengthening can help people with knee osteoarthritis feel less pain and improve their movement.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 65 Years |
| Sex | All |
| Enrollment | 46 (estimated) |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | January 4, 2024 |
| Main results expected | January 7, 2025 |
| Study ends | January 7, 2025 |
| Registry record updated | November 14, 2024 |
| Trial ID | NCT06658249 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 40-65 with grade 1-2 knee osteoarthritis and difficulty in walking or stair climbing.
✕Probably not a fit
Patients with a history of knee surgery, fractures, or inflammatory arthritis may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of core stabilization exercises compared to a foot-ankle strengthening program in patients suffering from knee osteoarthritis. Conducted at multiple physiotherapy clinics in Lahore, the study will involve 46 participants aged 40-65 with grade 1-2 knee OA. Participants will be randomly assigned to either the core stabilization group or the foot-ankle strengthening group, with treatments administered three times a week for six weeks. Outcomes will be measured using various questionnaires to assess pain, physical function, and quality of life before and after the intervention.
Why it matters
Potential benefit: If successful, this study could improve pain management and enhance the quality of life for patients with knee osteoarthritis.
How similar studies have gone: Previous studies have shown positive outcomes with similar exercise interventions for knee osteoarthritis, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Both genders of 40-65 years of age will include in this study. * Knee OA of grade 1-2. * Individuals with significant unilateral and bilateral knee osteoarthritis. symptoms and positive radio-graphical findings. * Difficulty in walking/stair climbing. Exclusion Criteria: * Any history of knee fracture/ tumor/ infection and hip/knee surgery. * Total Knee Replacement patients. * Neurological disease. * Patient received physical therapy treatment from last 6 months. * Inflammatory Arthritis (Rheumatoid Arthritis) * Use of any intra-articular injections (steroid/ hyaluronic acid/ PRP.) from last 3-6 months.
Where it's running
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Fatima Memorial Hospital Physical Therapy Department
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Ali Raza, MS-OMPT — Riphah International University
- Study coordinator: Imran Amjad, Phd
- Email: Imran.amjad@riphah.edu.pk
- Phone: 03324390125
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Platelet-rich plasma added to hyaluronic acid for knee osteoarthritis
This study tests whether a single injection of hyaluronic acid plus autologous platelet-rich plasma helps reduce knee OA symptoms more than hyaluronic acid alone in adults with moderate knee OA.
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Hyaluronic Acid Plus PRP Injection for Knee Osteoarthritis
This study tests whether a single HA injection combined with a patient’s own PRP is better at easing knee OA pain than HA alone.
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Weekly NNC0487-0111 injections for weight loss and knee pain in adults with excess weight and knee osteoarthritis
This will try weekly NNC0487-0111 injections versus placebo to see if adults with excess body weight and knee osteoarthritis can lose weight and have less knee pain.
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Altered Joint Mechanics and Biological Response in Osteoarthritic Knees
This study tests how braces or high tibial osteotomy (HTO) affect knee bone and cartilage in people with knee OA who are scheduled for corrective treatment.
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Why walking causes different amounts of knee pain in people with osteoarthritis
This project will see if differences in the brain, joint imaging, movement, and sensory responses explain why adults 45–80 with knee osteoarthritis have different levels of walking pain.
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Using anti-inflammatories and dextrose injections to treat knee osteoarthritis
This study is testing whether combining anti-inflammatory medication with dextrose injections can help adults aged 45-75 with knee osteoarthritis feel less pain.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.