Comparing core stabilization exercises and foot-ankle strengthening for knee osteoarthritis

Comparative Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program on Pain, Physical Function and Quality of Life in Patients With Knee Osteoarthritis.

Not applicable Interventional Riphah International University · NCT06658249

This study is testing whether core stabilization exercises or foot-ankle strengthening can help people with knee osteoarthritis feel less pain and improve their movement.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment46 (estimated)
Ages40 Years to 65 Years
SexAll
SponsorRiphah International University Academic / other
Locations1 site (Lahore, Punjab Province)
Trial IDNCT06658249 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of core stabilization exercises compared to a foot-ankle strengthening program in patients suffering from knee osteoarthritis. Conducted at multiple physiotherapy clinics in Lahore, the study will involve 46 participants aged 40-65 with grade 1-2 knee OA. Participants will be randomly assigned to either the core stabilization group or the foot-ankle strengthening group, with treatments administered three times a week for six weeks. Outcomes will be measured using various questionnaires to assess pain, physical function, and quality of life before and after the intervention.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 40-65 with grade 1-2 knee osteoarthritis and difficulty in walking or stair climbing.

Not a fit: Patients with a history of knee surgery, fractures, or inflammatory arthritis may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve pain management and enhance the quality of life for patients with knee osteoarthritis.

How similar studies have performed: Previous studies have shown positive outcomes with similar exercise interventions for knee osteoarthritis, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Both genders of 40-65 years of age will include in this study.
* Knee OA of grade 1-2.
* Individuals with significant unilateral and bilateral knee osteoarthritis. symptoms and positive radio-graphical findings.
* Difficulty in walking/stair climbing.

Exclusion Criteria:

* Any history of knee fracture/ tumor/ infection and hip/knee surgery.
* Total Knee Replacement patients.
* Neurological disease.
* Patient received physical therapy treatment from last 6 months.
* Inflammatory Arthritis (Rheumatoid Arthritis)
* Use of any intra-articular injections (steroid/ hyaluronic acid/ PRP.) from last 3-6 months.

Where this trial is running

Lahore, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knee OsteoarthritisPainPhysical FunctionQuality of Life
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.