Clinical trial Recruiting at 1 site Interventional Ages 40 to 65

Comparing core stabilization exercises and foot-ankle strengthening for knee osteoarthritis

Official title: Comparative Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program on Pain, Physical Function and Quality of Life in Patients With Knee Osteoarthritis.

Run by Riphah International University · NCT06658249 · Data updated 2026-11-12

This study is testing whether core stabilization exercises or foot-ankle strengthening can help people with knee osteoarthritis feel less pain and improve their movement.

Quick facts

Study typeInterventional
Ages40 Years to 65 Years
SexAll
Enrollment46 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedJanuary 4, 2024
Main results expectedJanuary 7, 2025
Study endsJanuary 7, 2025
Registry record updatedNovember 14, 2024
Trial IDNCT06658249 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 40-65 with grade 1-2 knee osteoarthritis and difficulty in walking or stair climbing.

Probably not a fit

Patients with a history of knee surgery, fractures, or inflammatory arthritis may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of core stabilization exercises compared to a foot-ankle strengthening program in patients suffering from knee osteoarthritis. Conducted at multiple physiotherapy clinics in Lahore, the study will involve 46 participants aged 40-65 with grade 1-2 knee OA. Participants will be randomly assigned to either the core stabilization group or the foot-ankle strengthening group, with treatments administered three times a week for six weeks. Outcomes will be measured using various questionnaires to assess pain, physical function, and quality of life before and after the intervention.

Why it matters

Potential benefit: If successful, this study could improve pain management and enhance the quality of life for patients with knee osteoarthritis.

How similar studies have gone: Previous studies have shown positive outcomes with similar exercise interventions for knee osteoarthritis, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Both genders of 40-65 years of age will include in this study.
* Knee OA of grade 1-2.
* Individuals with significant unilateral and bilateral knee osteoarthritis. symptoms and positive radio-graphical findings.
* Difficulty in walking/stair climbing.

Exclusion Criteria:

* Any history of knee fracture/ tumor/ infection and hip/knee surgery.
* Total Knee Replacement patients.
* Neurological disease.
* Patient received physical therapy treatment from last 6 months.
* Inflammatory Arthritis (Rheumatoid Arthritis)
* Use of any intra-articular injections (steroid/ hyaluronic acid/ PRP.) from last 3-6 months.

Where it's running

  • Fatima Memorial Hospital Physical Therapy Department
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.