Improving detection of immune-related side effects in cancer patients
Informatics strategies to improve immune-related adverse event detection in cancer patients
This study is looking to make it easier to spot side effects that can happen to cancer patients using new immune treatments, so if you join, your health records will help us learn how to better track and understand these issues for better care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10979489 on NIH RePORTER |
What this research studies
This research focuses on enhancing the detection of immune-related adverse events (irAEs) that can occur in cancer patients treated with immune checkpoint inhibitors. By utilizing advanced informatics technologies, particularly natural language processing, the project aims to automatically identify and monitor these side effects from electronic health records (EHR). The goal is to improve the understanding of irAE rates and severity, ultimately leading to better clinical care and patient outcomes. Patients participating in this research may contribute to a clinical trial that assesses the effectiveness of these automated detection methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who have been treated with immune checkpoint inhibitors and may experience immune-related adverse events.
Not a fit: Patients who have not received immune checkpoint inhibitors or do not experience immune-related adverse events may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification and management of immune-related side effects, enhancing the quality of life for cancer patients.
How similar studies have performed: Other research has shown promise in using informatics and natural language processing for adverse event detection, indicating that this approach could be effective.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Bitterman, Danielle S — Brigham and Women's Hospital
- Study coordinator: Bitterman, Danielle S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.