Investigating hot flashes and their impact on women's vascular health
Hot Flashes and Neurovascular Function in Women
NA · Mayo Clinic · NCT05193968
This study is testing how hot flashes might affect women's heart and blood vessel health, especially during menopause, to see if they increase the risk of high blood pressure and heart disease.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | Female |
| Sponsor | Mayo Clinic (other) |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT05193968 on ClinicalTrials.gov |
What this trial studies
This study examines the relationship between hot flashes and neurovascular function in women, particularly focusing on how these symptoms may increase the risk of hypertension and cardiovascular disease. It involves the use of various sympathoexcitatory stressors and medications to assess neurovascular control mechanisms. By understanding these connections, the research aims to provide insights into the cardiovascular risks associated with menopause. The study is conducted at the Mayo Clinic in Rochester, Minnesota.
Who should consider this trial
Good fit: Ideal candidates for this study are non-smoking, non-obese women who have at least one ovary and are free from cardiovascular disease.
Not a fit: Patients with existing cardiovascular disease or those taking medications that influence cardiovascular function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of cardiovascular risks in women experiencing hot flashes.
How similar studies have performed: Other studies have indicated a potential link between menopausal symptoms and cardiovascular health, suggesting that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Non-smokers. * Non-obese. * Have at least one ovary. * Free from cardiovascular disease. * Not taking medications influencing cardiovascular function. Exclusion Criteria: \- None.
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: Sarah Baker, PhD — Mayo Clinic
- Study coordinator: Pamela A Engrav
- Email: engrav.pamela@mayo.edu
- Phone: 507-255-6938
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hot Flashes, Menopause, Vasomotor System, Labile, Neurovascular function, Autonomic function, Microvascular Function