Condition

HLH clinical trials and research

• 6Clinical trials
• 4Countries

Newest HLH clinical trials

All recruiting trials (6)

• National Egyptian HLH Registry for pediatric patients

  A national HLH registry is being created in Egypt to collect information about pediatric HLH patients to improve understanding and care.

  Recruiting Ain Shams University · Cairo and 1 other locations · NCT07800234

• Observing gut health in children with leukemia

  This study looks at how leukemia treatment affects gut health and recovery in children aged 0-16 to see if nutrition plays a role in their healing process.

  Recruiting Great Ormond Street Hospital for Children NHS Foundation Trust · London · NCT06899581

• Using CD45RA Depleted Stem Cells to Prevent Infections After Transplant

  This study is testing whether using special stem cells can help patients with high-risk leukemia recover their immune system faster and prevent infections after a stem cell transplant.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06839456

• Validation of the OHI Index for Hematologic Malignancies

  This study is testing a new index to see if it can help doctors better understand and predict outcomes for patients with blood cancers who might develop a serious condition called HLH.

  Recruiting at 2 sites Meir Medical Center · Kfar Saba and 1 other locations · NCT05882175

• Using Tadekinig Alfa to treat severe side effects from CAR T cell therapy

  This study is testing if a new drug called Tadekinig alfa can help people who have severe side effects from CAR T cell therapy feel better.

  Recruiting Early Phase 1 University of Pennsylvania · Philadelphia, Pennsylvania · NCT05306080

• Cord blood transplant for children and young adults with blood cancers and disorders

  This study is testing a new treatment using chemotherapy followed by a cord blood transplant to see if it can help children and young adults with serious blood cancers and disorders who don't have a matched donor.

  Recruiting Phase 2 Memorial Sloan Kettering Cancer Center · New York, New York · NCT04644016

Related topics

Quick answers

How many HLH clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (3 trials), United Kingdom (1 trial), Egypt (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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