Condition
High Risk Acute Myeloid Leukemia clinical trials and research
As of November 12, 2026, Find a Trial lists 6 High Risk Acute Myeloid Leukemia clinical trials that are recruiting, at sites in 2 countries (most in United States (3), China (3)). By phase: Phase 1/2 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 2Countries
Newest High Risk Acute Myeloid Leukemia clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Donor γδ T cell infusion to prevent relapse after stem cell transplant in high‑risk AML | — | Wuhan, Hubei | Recruiting | Nov 19, 2025 |
| Venetoclax-enhanced BUCY versus standard BUCY conditioning for high‑risk AML and MDS before allogeneic stem cell transplant | — | Hangzhou, Zhejiang | Recruiting | Sep 19, 2025 |
| Using CD45RA Depleted Stem Cells to Prevent Infections After Transplant | Phase 1/2 | Philadelphia, Pennsylvania | Recruiting | Feb 21, 2025 |
| Digital application for improving quality of life in acute leukemia patients | — | Boston, Massachusetts and 2 other locations | Recruiting | Jun 24, 2024 |
| Combining venetoclax and azacitidine with HAAG for treating newly diagnosed AML | Phase 2 | Suzhou, Jiangsu | Recruiting | May 1, 2024 |
| Comparing two types of palliative care for patients with acute myeloid leukemia | — | Birmingham, Alabama and 19 other locations | Recruiting | Feb 14, 2022 |
All recruiting trials (6)
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Donor γδ T cell infusion to prevent relapse after stem cell transplant in high‑risk AML
This will test whether a donor γδ T cell infusion given soon after an allogeneic stem cell transplant can help prevent relapse in adults (18–65) with high‑risk acute myeloid leukemia.
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Venetoclax-enhanced BUCY versus standard BUCY conditioning for high‑risk AML and MDS before allogeneic stem cell transplant
This will test whether adding venetoclax to BUCY conditioning before allogeneic stem cell transplant helps patients aged 12–60 with high‑risk AML or MDS stay in remission longer.
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Using CD45RA Depleted Stem Cells to Prevent Infections After Transplant
This study is testing whether using special stem cells can help patients with high-risk leukemia recover their immune system faster and prevent infections after a stem cell transplant.
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Digital application for improving quality of life in acute leukemia patients
This study is testing a digital app designed to help newly diagnosed acute myeloid leukemia patients improve their quality of life and cope better during their chemotherapy treatment.
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Combining venetoclax and azacitidine with HAAG for treating newly diagnosed AML
This study is testing a new combination of medications for people who have just been diagnosed with intermediate and high-risk acute myeloid leukemia to see if it helps them respond better to treatment.
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Comparing two types of palliative care for patients with acute myeloid leukemia
This study is testing if regular palliative care can help hospitalized patients with acute myeloid leukemia feel better and cope with their illness just as well as specialty palliative care.
Related topics
Quick answers
How many High Risk Acute Myeloid Leukemia clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (3 trials), China (3 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.