Condition

Healthy Controls clinical trials and research

• 25Clinical trials
• 1NIH research projects
• 8Countries

Newest Healthy Controls clinical trials

All recruiting trials (25)

• Accessory breathing muscles in people with chronic neck pain

  This study compares how accessory chest and neck muscles work in people with chronic neck pain vs. healthy individuals to see how they relate to diaphragm function and overall breathing.

  Recruiting Kocaeli Sağlık ve Teknoloji Üniversitesi · Kocaeli, Derince · NCT07782099

• Multiomic data study in South Carolina Medicaid patients with Type 2 diabetes and healthy controls

  This study tests whether combining genetic, molecular, clinical, wearable, and lifestyle data in SC Medicaid patients with Type 2 diabetes, and in healthy controls, can help predict kidney disease and diabetes progression.

  Recruiting at 2 sites Guardian Research Network, Inc. · Orangeburg, South Carolina and 1 other locations · NCT07731399

• Effects of exogenous ketones on brain energy and thinking in older adults with prediabetes

  In older adults with prediabetes, researchers will test if a single dose of a ketone supplement can boost brain energy use and processing speed compared with people with normal blood sugar.

  Recruiting at 2 sites University of Alabama at Birmingham · Birmingham, Alabama and 1 other locations · NCT07546409

• Safety and tolerability testing of VVZ-2471 in healthy adults

  This study tests whether VVZ-2471 is safe and tolerable in healthy adults who don’t use illicit drugs.

  Recruiting Phase 1 Virginia Commonwealth University · Richmond, Virginia · NCT07531316

• Immediate effects of graded motor imagery for chronic ankle instability

  This trial will test whether graded motor imagery produces quick improvements in pain, muscle strength, stiffness, function, and perceived stability for adults with chronic ankle instability compared with healthy people.

  Recruiting Istanbul University - Cerrahpasa · Istanbul · NCT07376915

• Ultralow-dose PET imaging of somatostatin receptor 2 (SSTR2) uptake

  This study will test whether an ultralow-dose 68Ga-Dotatate PET scan on a high-sensitivity scanner can detect SSTR2 uptake in adults with and without neuroendocrine tumors.

  Recruiting Phase 2 Nuclear Imaging Institute · Englewood, New Jersey · NCT07284589

• Cholinergic degeneration and cognitive fluctuations in Lewy body dementias

  This project will test whether loss of cholinergic neurons is linked to cognitive fluctuations in people with Lewy body dementias using blood and skin biomarkers, multimodal MRI, prolonged EEG, and will try an 8‑week galantamine treatment in a small subgroup.

  Recruiting Phase 4 Virginia Commonwealth University · Richmond, Virginia · NCT07284290

• DANU Smart Socks to measure walking and balance in Parkinson's

  This project will test whether DANU Smart Socks can measure walking and balance in people with Parkinson's and compare their results with healthy adults of similar age.

  Recruiting Northumbria University · Newcastle upon Tyne, Tyne and Wear and 1 other locations · NCT07281794

• Comparing physical and psychosocial health in people with Takayasu arteritis, Behçet's disease, and healthy adults

  This will test whether adults with Takayasu arteritis or Behçet's disease have weaker respiratory and limb muscles, lower exercise capacity, or different quality of life and psychological well‑being compared with healthy adults.

  Recruiting Alanya Alaaddin Keykubat University · Denizli, Denizli · NCT07276087

• Impact of the brain’s adenosine pathway on epilepsy and arousal in adults

  This study tests how the brain’s adenosine system affects arousal and breathing in adults with drug-resistant focal epilepsy compared with healthy volunteers.

  Recruiting Hospices Civils de Lyon · Bron · NCT07249034

• Using brain scans and machine learning to track emotional ups and downs in bipolar disorder

  This project will test whether fMRI plus machine learning can read moment-by-moment emotions and whether boosting positive emotions can make mood and brain activity more stable in adults with bipolar I or II (currently depressed or mixed) compared with healthy volunteers.

  Recruiting Laureate Institute for Brain Research, Inc. · Tulsa, Oklahoma · NCT07221864

• Do antipsychotic drugs block insulin action in the brain?

  This project will test whether haloperidol blocks insulin action in the brain of healthy adults aged 18–35.

  Recruiting Phase 4 Centre for Addiction and Mental Health · Toronto, Ontario · NCT07109245

• Dose effects of low-intensity focused ultrasound on deep brain pathways

  This project will test whether different doses of low‑intensity focused ultrasound change deep brain connections in healthy adults.

  Recruiting Laureate Institute for Brain Research, Inc. · Tulsa, Oklahoma · NCT07099950

• PET‑MRI mapping of brainstem serotonin pathways in adults with Dravet syndrome

  This uses a PET‑MRI scan with the tracer [18F]MPPF to see if serotonin pathways in the brainstem differ in adults with Dravet syndrome compared with healthy controls.

  Recruiting Hospices Civils de Lyon · Bron, Rhone · NCT07013331

• Developing digital tools for diagnosing and monitoring Parkinson's disease

  This study is testing new digital tools that use eye and walking data to see if they can help doctors diagnose and monitor Parkinson's disease more accurately.

  Recruiting University of Exeter · Exeter · NCT06733077

• Subthreshold vestibular stimulation to improve balance and motion perception

  This test will see if very-low-level (subthreshold) vestibular stimulation, alone or combined with balance training, helps adults with unilateral or bilateral vestibular hypofunction and healthy adults improve balance and motion perception.

  Recruiting Creighton University · Omaha, Nebraska · NCT06732440

• Using transcranial interference stimulation to assess social cognition

  This study is testing a new brain stimulation technique to see if it can safely help improve social thinking skills in healthy people, with hopes of using it for treating serious mental health conditions in the future.

  Recruiting Columbia University · New York, New York · NCT06607432

• Understanding how to treat individuals at high risk for psychosis

  This study is testing different treatments, like brain stimulation and mindfulness techniques, to see if they can help people who are at high risk of developing psychosis.

  Recruiting Beth Israel Deaconess Medical Center · Shanghai, Shanghai Municipality · NCT06542640

• Heat and cold therapy for reducing depression symptoms

  This study is testing whether a combination of heat therapy and a cold water plunge can help reduce depression symptoms in adults with major depressive disorder.

  Recruiting Vail Health Behavioral Health · Edwards, Colorado · NCT06263738

• Evaluating a new PET imaging agent for brain conditions

  This study is testing a new imaging agent to see if it can help detect certain brain changes in people with Parkinson's disease, Multiple System Atrophy, and Dementia with Lewy Bodies, as well as in healthy individuals.

  Recruiting Early Phase 1 Massachusetts General Hospital · Charlestown, Massachusetts · NCT06098612

• High-Intensity Interval Training for COPD and Healthy Individuals

  This study is testing whether a special type of intense exercise can help people with COPD and healthy individuals improve their thinking skills, fitness, and muscle strength over 12 weeks.

  Recruiting at 2 sites Umeå University · Hasselt, Diepenbeek and 1 other locations · NCT06068322

• Collecting microbiome samples to study health and disease

  This study is collecting samples from people of all ages to learn more about how our gut bacteria affect our health and diseases.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05656378

• Development of a new eye-tracking software for Alzheimer's Disease

  This study is testing a new eye-tracking software to see if it can help measure brain function changes in people with Alzheimer's Disease.

  Recruiting at 4 sites McGill University · Montreal, Quebec and 4 other locations · NCT05176704

• Evaluating the effects of HA35 on gut permeability and muscle response to alcohol

  This study is testing if a treatment called HA35 can improve gut health and how muscles respond to alcohol in healthy people.

  Recruiting Early Phase 1 The Cleveland Clinic · Cleveland, Ohio · NCT05025865

• Understanding visceral sensitivity in IBS and IBD

  This study is trying to understand how the body reacts to gut sensations in people with Irritable Bowel Syndrome, active and inactive Inflammatory Bowel Disease, and healthy individuals by collecting samples and measuring different body responses.

  Recruiting KU Leuven · Leuven, Vlaams-Brabant · NCT02421705

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Effects of folic acid supplements during pregnancy on mental health in youth

  This study looks at how taking folic acid supplements before and during pregnancy might help improve the mental health of kids and teens, especially in reducing the risk of conditions like autism and psychosis, by comparing those with and without psychiatric symptoms.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10852967

Related topics

Quick answers

How many Healthy Controls clinical trials are recruiting right now?

25, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (13 trials), Turkey (Türkiye) (3 trials), France (2 trials), United Kingdom (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Early Phase 1: 2, Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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