Comparing physical and psychosocial health in people with Takayasu arteritis, Behçet's disease, and healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a cross-sectional, case-control observational study comparing adults with Takayasu arteritis, adults with Behçet's disease, and healthy controls. Participants will undergo standardized measurements of respiratory muscle strength (maximal inspiratory/expiratory pressures), peripheral muscle strength (handgrip and limb dynamometry), functional capacity tests (six-minute walk test, squat test), body composition, and validated questionnaires on quality of life, illness perception, and psychological status. Data will be compared across the three groups to characterize physical performance and psychosocial impact associated with each vasculitis. The protocol excludes pregnant individuals, those with major psychiatric or neurological disorders, or cognitive impairment that would interfere with participation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Inclusion Criteria (Takayasu Arteritis Group):

* Age 18 years or older.
* Diagnosis of Takayasu arteritis according to the American College of Rheumatology (ACR) classification criteria.
* Voluntary participation with written informed consent.

Inclusion Criteria (Behçet's Disease Group):

* Age 18 years or older.
* Diagnosis of Behçet's disease according to the International Study Group for Behçet's Disease criteria.
* Voluntary participation with written informed consent.

Inclusion Criteria (Healthy Control Group):

* Age 18 years or older.
* No history of systemic, rheumatologic, or chronic inflammatory disease.
* Voluntary participation with written informed consent.

Exclusion Criteria:

Exclusion Criteria (Patient Groups - Takayasu Arteritis and Behçet's Disease):

* Pregnancy.
* Presence of psychiatric disorder or ongoing psychiatric treatment.
* Cognitive impairment that may interfere with participation.
* Presence of neurological disease (e.g., hemiplegia, Parkinson's disease, multiple sclerosis, vertigo, epilepsy, etc.).
* History of any surgical operation within the past year.
* Coexisting rheumatic disease other than Takayasu arteritis or Behçet's disease.

Exclusion Criteria (Healthy Control Group):

* Pregnancy.
* Presence of psychiatric disorder or ongoing psychiatric treatment.
* Cognitive impairment that may interfere with participation.
* Presence of neurological disease (e.g., hemiplegia, Parkinson's disease, multiple sclerosis, vertigo, epilepsy, etc.).
* History of any surgical operation within the past year.
* History of rheumatologic or chronic inflammatory disease.

Where it's running

• Pamukkale University
  Denizli, Denizli, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Özlem Nur Tok Yaman, MSc
• Email: ozlem.tok@alanya.edu.tr
• Phone: +90-242-5106060

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.