Optic nerve sheath ultrasound for diagnosing giant cell arteritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study uses orbital ultrasound to measure optic nerve sheath thickness in patients older than 50 who present with suspected giant cell arteritis at three French hospitals. Measurements will be obtained early in the diagnostic workup and compared with the standard diagnostic pathway (clinical evaluation, other imaging and/or temporal artery biopsy) to determine diagnostic accuracy. Patients who have recently received high-dose corticosteroids or who have certain eye or neurologic conditions are excluded because these factors can affect imaging. The goal is to determine whether this quick, non-invasive, widely available ultrasound marker can shorten time to diagnosis and reduce reliance on more invasive or less accessible tests.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with suspected GCA
* Patient over 50 years

Exclusion Criteria:

* Patient with history of GCA
* Patient with a history of polymyalgia rheumatic (PMR) without initial PET scan
* Patient with a history of retinal disease, demyelinating disease, or intracranial hypertension
* Use of corticosteroids \> 0.5mg/kg in the last 2 weeks

Where it's running

• Internal Medecine Department- CHU Caen
  Caen, France Recruiting
• Rhumatology departement - Centre Hospitalier Aix en Provence
  Aix-en-Provence, France Not yet recruiting
• Rhumatology department - Centre Hospitalier Universitaire de Brest
  Brest, France Not yet recruiting
• Internal Medicine and Clinical Immulogy department - Centre Hospitalier Universitaire de Dijon
  Dijon, France Not yet recruiting
• Internal Medicine and VascularMedecine Department - Centre Hospitalier Universitaire de Nantes
  Nantes, France Not yet recruiting
• Internal Medicine department - Hôpital Saint-Antoine
  Paris, France Not yet recruiting

Study contacts

• Principal investigator: Omar AL TABAA, Dr — Hôpital NOVO
• Study coordinator: Maryline DELATTRE
• Email: maryline.delattre@ght-novo.fr
• Phone: +330130754131

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Stopping versus reducing tocilizumab for people with well-controlled giant cell arteritis

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• Halo sign in GCA: how soon after steroids to perform Doppler ultrasound

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.