Drug or treatment

Tocilizumab clinical trials

• 24Clinical trials
• 25Countries

Newest trials

All recruiting trials (24)

• Anticoagulation Plus Tocilizumab for Acute Cerebral Venous Thrombosis

  This study tests whether adding a single dose of tocilizumab to standard blood thinners helps people with acute cerebral venous thrombosis.

  Recruiting Capital Medical University · Beijing, Beijing Municipality · NCT07801638

• Linvoseltamab with pre-dose Tocilizumab to reduce CRS in adults with relapsed/refractory multiple myeloma

  This study tests whether giving tocilizumab before the first dose of linvoseltamab can lower the risk of cytokine release syndrome in adults with relapsed/refractory multiple myeloma who have had at least four prior therapies.

  Recruiting at 7 sites Phase 4 Regeneron Pharmaceuticals · Los Angeles, California and 6 other locations · NCT07609940

• Preventing Cytokine Release Syndrome with a single dose of tocilizumab before ramantamig in multiple myeloma

  A single pre-treatment dose of tocilizumab is being tested to see if it can prevent or lessen cytokine release syndrome in people with relapsed or refractory multiple myeloma who are treated with ramantamig.

  Recruiting at 60 sites Phase 2 Janssen Research & Development, LLC · Goodyear, Arizona and 59 other locations · NCT07589634

• Tocilizumab treatment for anti-MDA5 positive dermatomyositis in adults

  This study will try giving tocilizumab or a placebo to adults with anti-MDA5 positive dermatomyositis to see if it improves symptoms and breathing.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07377058

• IL-6 guided dexamethasone or tocilizumab treatment for hospitalized acute hypoxemic respiratory failure

  This study will test whether measuring IL-6 to guide early treatment with dexamethasone or tocilizumab helps adults hospitalized with new acute hypoxemic respiratory failure.

  Recruiting Phase 2 University Health Network, Toronto · Toronto, Ontario · NCT07334379

• Stopping versus reducing tocilizumab for people with well-controlled giant cell arteritis

  This trial will test whether stopping tocilizumab or reducing its dose better maintains remission in people with giant cell arteritis who have been on high-dose tocilizumab for at least 12 months and off steroids for at least three months.

  Recruiting at 7 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Atlanta, Georgia and 6 other locations · NCT07108387

• Tocilizumab plus standard therapy for chronic antibody-mediated rejection after kidney transplant

  This trial will try adding tocilizumab to standard treatment (plasmapheresis, IVIG, and rituximab) to see if it helps people with chronic active antibody-mediated rejection of a kidney transplant.

  Recruiting Shahid Beheshti University of Medical Sciences · Tehran · NCT07006532

• Combining Tocilizumab and Flupentixol-Melitracen for Thyroid Eye Disease Treatment

  This study is testing if combining two medications, Tocilizumab and Flupentixol-Melitracen, can help people with thyroid eye disease feel better and improve their eye symptoms.

  Recruiting Phase 4 Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai, Shanghai Municipality · NCT06927375

• Tocilizumab-aazg to reduce stroke risk after a ruptured brain aneurysm

  This trial will try to see if a single IV dose of tocilizumab-aazg is safe and can help prevent delayed strokes in adults who have had a ruptured brain aneurysm (aneurysmal subarachnoid hemorrhage).

  Recruiting Phase 1 University of Florida · Gainesville, Florida · NCT06863480

• Tocilizumab for Acute Chest Syndrome in Sickle Cell Disease

  This study tests whether a single infusion of tocilizumab can help people with sickle cell disease and acute chest syndrome come off oxygen and respiratory support faster.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Paris · NCT06818266

• Investigating Vitamin B12 Levels in Patients on Tocilizumab

  This study is trying to see if vitamin B12 levels change in patients with autoimmune diseases who are being treated with tocilizumab during flare-ups compared to when they're feeling better.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT06654154

• Prophylactic use of Tocilizumab to prevent complications after CAR-T therapy

  This study is testing if giving Tocilizumab before or during CAR-T therapy can help prevent serious side effects like cytokine release syndrome and neurotoxicity in patients with B-cell cancers.

  Recruiting Phase 2 Insel Gruppe AG, University Hospital Bern · Bern, Canton of Bern · NCT06430736

• Nintedanib plus tocilizumab for systemic sclerosis with interstitial lung disease

  This trial will test whether combining nintedanib and tocilizumab helps adults with systemic sclerosis and interstitial lung disease do better than standard treatments over 56 weeks.

  Recruiting Phase 3 National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland · Warsaw, Masovian Voivodeship · NCT06297096

• Using Tocilizumab for treating aortitis in Giant Cell Arteritis

  This study is testing if a new version of Tocilizumab can safely help people with Giant Cell Arteritis and active aortitis feel better while they are already on standard treatment.

  Recruiting Groupe français d'étude des Maladies Inflammatoires de loeil · Paris · NCT06271018

• Using Tocilizumab to improve outcomes in lung transplant patients

  This study is testing if adding Tocilizumab to the usual treatment can help lung transplant patients have better health outcomes compared to those who get a placebo.

  Recruiting at 13 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Phoenix, Arizona and 20 other locations · NCT06033196

• Infusing tocilizumab into chest and abdominal cavities for advanced cancer patients

  This study is testing if giving tocilizumab directly into the chest and abdomen can help advanced cancer patients with fluid buildup feel better and respond to treatment.

  Recruiting Phase 1 Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Pittsburgh, Pennsylvania · NCT06016179

• Chemotherapy with or without Tocilizumab for certain types of breast cancer

  This study is testing if adding a drug called tocilizumab to standard chemotherapy helps people with certain types of advanced breast cancer feel better compared to just chemotherapy alone.

  Recruiting at 7 sites Phase 2 Indiana University · Atlanta, Georgia and 6 other locations · NCT05846789

• Combining tocilizumab and tofacitinib for treating vascular Behçet's syndrome

  This study is testing if combining two newer medications, tocilizumab and tofacitinib, with steroids can help people with vascular Behçet's syndrome feel better compared to the usual treatment.

  Recruiting Phase 2 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT05845723

• Using tocilizumab to treat acute chest syndrome in sickle cell disease

  This study is testing if a low dose of tocilizumab can help people with sickle cell disease who have acute chest syndrome feel better during their hospital stay.

  Recruiting Phase 2 University of Chicago · Chicago, Illinois · NCT05640271

• Evaluating Upadacitinib and Tocilizumab for Treating Systemic Juvenile Idiopathic Arthritis in Children

  This study is testing whether a new drug called upadacitinib is safe and effective for children and teens with systemic juvenile idiopathic arthritis compared to an existing treatment called tocilizumab.

  Recruiting at 40 sites Phase 3 AbbVie · Phoenix, Arizona and 44 other locations · NCT05609630

• Using ACTEMRA to treat pediatric brain tumors

  This study is testing if the drug ACTEMRA can help children and young adults with a specific type of brain tumor feel better and improve their quality of life.

  Recruiting at 13 sites Phase 2 Nationwide Children's Hospital · Aurora, Colorado and 13 other locations · NCT05233397

• Using Tocilizumab to treat Generalized Myasthenia Gravis

  This study is testing if Tocilizumab can help people with Generalized Myasthenia Gravis who have anti-AChR antibodies feel better and improve their symptoms.

  Recruiting Phase 2 Tang-Du Hospital · Beijing, Beijing Municipality and 5 other locations · NCT05067348

• Combining tocilizumab and atezolizumab for advanced lung cancer after previous treatments

  This study is testing if combining two medications, tocilizumab and atezolizumab, can help adults with advanced lung cancer that hasn't improved with previous treatments.

  Recruiting Phase 1/2 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT04691817

• Evaluating treatments for severe Takayasu arteritis

  This study tests whether tocilizumab or adalimumab is more effective for people with severe Takayasu arteritis to help tailor treatments based on their specific needs.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT04300686

Quick answers

How many clinical trials of Tocilizumab are recruiting right now?

24, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 25 countries. The most sites are in United States (11 trials), China (7 trials), France (4 trials), Australia (3 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 10, Phase 3: 3, Phase 4: 3, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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