Condition

Focal Segmental Glomerulosclerosis clinical trials and research

• 15Clinical trials
• 44Countries

Newest Focal Segmental Glomerulosclerosis clinical trials

All recruiting trials (15)

• Praliciguat treatment for adults with focal segmental glomerulosclerosis (FSGS)

  This will test if praliciguat lowers urine protein in adults with biopsy-confirmed FSGS.

  Recruiting at 31 sites Phase 2 Akebia Therapeutics · Chula Vista, California and 31 other locations · NCT07268638

• BI 764198 for adults and adolescents with focal segmental glomerulosclerosis (FSGS).

  This study will test BI 764198 tablets taken once daily for up to two years in adults and adolescents with FSGS to see if it lowers urine protein and preserves kidney function.

  Recruiting at 253 sites Phase 3 Boehringer Ingelheim · Alabaster, Alabama and 314 other locations · NCT07220083

• Testing ManNAc for treating kidney disease FSGS

  This study is testing if a new oral treatment called ManNAc can help adults with kidney disease FSGS by reducing protein levels in their urine and checking how safe it is over 12 weeks.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06664814

• Evaluating treatments for kidney diseases in young to middle-aged adults

  This study is testing three different treatments for kidney diseases in young to middle-aged adults to see if they can reduce protein levels in urine and help with symptoms over 24 weeks.

  Recruiting at 78 sites Phase 2 Sanofi · Birmingham, Alabama and 78 other locations · NCT06500702

• Registry and biobank for resistant nephrotic syndrome treatment responses

  This study is collecting information from patients with resistant nephrotic syndrome to see how different treatments work and to help find better options for the future.

  Recruiting Medical University of Vienna · Vienna · NCT06162546

• Using Metformin to Improve Kidney Health in FSGS

  This study is testing if taking extended-release Metformin along with regular treatment can help improve kidney health in people with Focal Segmental Glomerulosclerosis (FSGS).

  Recruiting at 2 sites Phase 1/2 Yale University · New Haven, Connecticut and 1 other locations · NCT06090227

• National Registry for Rare Kidney Diseases

  This study is collecting health information from people with rare kidney diseases to help improve treatments and create better care guidelines.

  Recruiting UK Kidney Association · Bristol, South West · NCT06065852

• Observational study on kidney transplant recurrence in FSGS and MCD

  This study is looking at patients with kidney diseases called FSGS and MCD who have had or will have a kidney transplant to see how often these diseases come back afterward.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05650619

• Vagus nerve stimulation for treating nephrotic syndrome in children

  This study is testing whether a new treatment using vagus nerve stimulation can help children aged 3 to 17 with nephrotic syndrome feel better and reduce their symptoms.

  Recruiting at 2 sites Northwell Health · New Hyde Park, New York and 1 other locations · NCT05588063

• Using vagus nerve stimulation to treat nephrotic syndrome in children

  This study is testing if a new type of nerve stimulation can help children with steroid-resistant nephrotic syndrome feel better over 26 weeks.

  Recruiting at 2 sites Northwell Health · New Hyde Park, New York and 1 other locations · NCT05583942

• Treatment of pediatric kidney diseases with Sparsentan

  This study is testing if a new oral medication called Sparsentan can help children aged 1 to 18 with certain kidney diseases feel better and improve their condition over two years.

  Recruiting at 38 sites Phase 2 Travere Therapeutics, Inc. · Los Angeles, California and 46 other locations · NCT05003986

• NEPTUNE Match: Personalized matching of patients to kidney treatment options

  This project will try a system that matches people in the NEPTUNE cohort who have nephrotic syndromes or related kidney diseases with suitable clinical trials and shares those matches with patients and their doctors.

  Recruiting at 15 sites University of Michigan · Atlanta, Georgia and 15 other locations · NCT04571658

• Treatment for drug-resistant FSGS using the LIPOSORBER® LA-15 System

  This study is testing a new treatment using the LIPOSORBER® LA-15 System to see if it can help adults with nephrotic syndrome caused by FSGS when other treatments haven't worked or can't be used.

  Recruiting at 10 sites Kaneka Medical America LLC · Loma Linda, California and 9 other locations · NCT04065438

• A network for analyzing kidney biopsy data in glomerular diseases

  This study is trying to build a detailed database of kidney biopsy samples and health information from patients with glomerular diseases to help researchers better understand these conditions and improve treatments.

  Recruiting at 6 sites Seoul National University Hospital · Chuncheon and 5 other locations · NCT03929887

• Blood purification therapy for children with Focal Segmental Glomerulosclerosis

  This study is testing a blood purification treatment to see if it can help children with Focal Segmental Glomerulosclerosis feel better when other treatments haven't worked.

  Recruiting at 10 sites Kaneka Medical America LLC · Loma Linda, California and 11 other locations · NCT02235857

Related topics

Quick answers

How many Focal Segmental Glomerulosclerosis clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 44 countries. The most sites are in United States (11 trials), Germany (3 trials), Italy (3 trials), Netherlands (3 trials), Poland (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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