Clinical trial Recruiting at 6 sites Observational

A network for analyzing kidney biopsy data in glomerular diseases

Official title: Multicenter Prospective Cohort of Kidney Biopsy for Glomerular Disease Research

Run by Seoul National University Hospital · NCT03929887 · Data updated 2026-11-12

This study is trying to build a detailed database of kidney biopsy samples and health information from patients with glomerular diseases to help researchers better understand these conditions and improve treatments.

Quick facts

Study typeObservational
SexAll
Enrollment3000 (estimated)
SponsorSeoul National University Hospital
Academic / other
Locations6 sites (Chuncheon and 5 other locations)
StatusRecruiting
StartedMay 1, 2019
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedFebruary 12, 2020
Trial IDNCT03929887 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients suspected of glomerular disease who are undergoing kidney biopsy at participating medical centers.

Probably not a fit

Patients who have previously received a kidney transplant will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a comprehensive database of kidney biopsy samples and associated clinical data for patients with glomerular diseases such as Minimal Change Disease and IgA Nephropathy. By leveraging advances in molecular analysis and bioinformatics, the study seeks to enhance understanding of the biology of glomerulonephritis and improve precision medicine approaches in nephrology. The Korean Kidney Biopsy Network (KORNERSTONE) will collect long-term observational data and genomic information from kidney tissues, which will be archived in a web-based platform for easy access by researchers.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment options for patients with glomerular diseases.

How similar studies have gone: Other studies utilizing genomic data from kidney biopsies have shown promise in advancing understanding and treatment of kidney diseases, suggesting this approach is both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
1. Inclusion criteria

   * Patient suspected of glomerular disease who received kidney biopsy in participating university medical centers
   * Children (age\<18 years) also included
2. Exclusion criteria - Patients who previously received a kidney transplant

Where it's running

  • KangWon National University Hospital
    Chuncheon, South Korea
    Recruiting
  • Keimyung University Dongsan Medical Center
    Daegu, South Korea
    Recruiting
  • Chung-Ang University Hosptial
    Seoul, South Korea
    Recruiting
  • Seoul National University Hospital
    Seoul, South Korea
    Recruiting
  • Severance Hospital
    Seoul, South Korea
    Recruiting
  • SMG-SNU Boramae Medical Center
    Seoul, South Korea
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Testing ManNAc for treating kidney disease FSGS

    This study is testing if a new oral treatment called ManNAc can help adults with kidney disease FSGS by reducing protein levels in their urine and checking how safe it is over 12 weeks.

    Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06664814

  • National Registry for Rare Kidney Diseases

    This study is collecting health information from people with rare kidney diseases to help improve treatments and create better care guidelines.

    Recruiting UK Kidney Association · Bristol, South West · NCT06065852

  • Exploring experiences of patients and parents dealing with swelling from Nephrotic Syndrome

    This study talks to patients and parents about their experiences with swelling from Nephrotic Syndrome to help create better ways to measure how new treatments work.

    Recruiting University of Michigan · Ann Arbor, Michigan · NCT05505500

  • NEPTUNE Match: Personalized matching of patients to kidney treatment options

    This project will try a system that matches people in the NEPTUNE cohort who have nephrotic syndromes or related kidney diseases with suitable clinical trials and shares those matches with patients and their doctors.

    Recruiting at 15 sites University of Michigan · Atlanta, Georgia and 15 other locations · NCT04571658

  • Observational study on kidney transplant recurrence in FSGS and MCD

    This study is looking at patients with kidney diseases called FSGS and MCD who have had or will have a kidney transplant to see how often these diseases come back afterward.

    Recruiting University of Michigan · Ann Arbor, Michigan · NCT05650619

  • Vagus nerve stimulation for treating nephrotic syndrome in children

    This study is testing whether a new treatment using vagus nerve stimulation can help children aged 3 to 17 with nephrotic syndrome feel better and reduce their symptoms.

    Recruiting at 2 sites Northwell Health · New Hyde Park, New York and 1 other locations · NCT05588063

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.