Condition

Desmoplastic Small Round Cell Tumor clinical trials and research

• 11Clinical trials
• 6Countries

Newest Desmoplastic Small Round Cell Tumor clinical trials

All recruiting trials (11)

• Lurbinectedin plus irinotecan for advanced desmoplastic small round cell tumor

  This study will try lurbinectedin combined with irinotecan in people 15 and older whose desmoplastic small round cell tumor has come back or spread after anthracycline chemotherapy.

  Recruiting at 6 sites Phase 2 Italian Sarcoma Group · Candiolo, Torino and 10 other locations · NCT07328425

• Combining immune therapy with chemotherapy for advanced soft tissue sarcoma

  This study is testing if combining a new immune therapy with standard chemotherapy can help people with advanced soft tissue sarcoma who can’t have surgery or radiation feel better and live longer.

  Recruiting Phase 2 Fudan University · Shanghai, Shanghai Municipality · NCT06849986

• Testing a new drug combination for treating relapsed or refractory sarcomas in adolescents and young adults

  This study is testing a new combination of drugs to see if it can help adolescents and young adults with tough-to-treat sarcomas feel better and improve their chances of recovery.

  Recruiting Phase 1/2 Dana-Farber Cancer Institute · Boston, Massachusetts and 2 other locations · NCT06709495

• Alpha/beta T‑Cell and B‑Cell Depletion plus Zoledronic Acid for Pediatric and Young Adult Solid Tumors

  This study will try removing alpha/beta T cells and B cells from donor stem cell grafts and giving zoledronic acid to see if it helps children and young adults (6 months to 25 years) with relapsed or high‑risk solid tumors tolerate allogeneic transplant and reduce relapse.

  Recruiting Phase 1/2 University of Florida · Gainesville, Florida · NCT06625190

• Using pasireotide to treat advanced synovial sarcoma and desmoplastic small round cell tumor

  This study is testing if the drug pasireotide can help young people with advanced synovial sarcoma and desmoplastic small round cell tumors stay healthy longer after their initial treatments.

  Recruiting Phase 2 University Hospital Heidelberg · Heidelberg, Baden-Wurttemberg and 3 other locations · NCT06456359

• MASCT-I plus doxorubicin and ifosfamide as first-line treatment for advanced soft tissue sarcoma

  This trial will test whether adding MASCT-I to standard chemotherapy (doxorubicin and ifosfamide) helps adults with advanced soft tissue sarcoma respond better or live longer.

  Recruiting Phase 2 HRYZ Biotech Co. · Guangzhou · NCT06277154

• Using lurbinectedin to treat specific tumors in children and young adults

  This study is testing if a new drug called lurbinectedin can help children and young adults with certain types of tumors, like Ewing sarcoma, by targeting the proteins that make the tumors grow.

  Recruiting at 6 sites Phase 1/2 Children's Hospital of Philadelphia · Los Angeles, California and 5 other locations · NCT05918640

• B7-H3 CAR T-cell therapy for pediatric solid tumors

  This study is testing a new type of immune therapy using specially modified T cells to see if it can help children with tough-to-treat solid tumors.

  Recruiting Phase 1 St. Jude Children's Research Hospital · Memphis, Tennessee · NCT04897321

• Registry collecting health information about Desmoplastic Small Round Cell Tumor

  This study is collecting health information from people with Desmoplastic Small Round Cell Tumor to help researchers learn more about the condition and improve future treatments.

  Recruiting Memorial Sloan Kettering Cancer Center · New York, New York · NCT04690374

• Trastuzumab Deruxtecan for Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

  This study tests trastuzumab deruxtecan in children and young adults whose osteosarcoma, Wilms tumor, or desmoplastic small round cell tumor has come back or resisted treatment to see if the drug can help shrink tumors.

  Recruiting at 21 sites Phase 2 National Cancer Institute (NCI) · Birmingham, Alabama and 31 other locations · NCT04616560

• Characterizing rare soft tissue sarcomas

  This study is trying to learn more about rare types of soft tissue sarcomas by collecting detailed information from 400 patients to help improve treatment options.

  Recruiting at 16 sites Institut Claudius Regaud · Besançon and 19 other locations · NCT03967834

Related topics

Quick answers

How many Desmoplastic Small Round Cell Tumor clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (6 trials), China (2 trials), Italy (1 trial), Spain (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1/2: 3, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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