Using modified Desmopressin for better imaging in Cushing syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on improving the diagnosis of Cushing syndrome, particularly distinguishing Cushing disease from ectopic Cushing syndrome. It utilizes a modified form of Desmopressin, radiolabeled with Gallium-68, for enhanced imaging through PET/CT scans. The goal is to provide clearer anatomical and functional information about pituitary tumors, which are often difficult to visualize accurately with current imaging techniques. By preparing a freeze-dried cold-kit for this purpose, the study aims to facilitate better surgical navigation during transsphenoidal surgery for affected patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients diagnosed with endogenous Cushing's syndrome
2. Patients in the age group of 5 to 75 years.
3. Patients willing to give informed consent.

Exclusion Criteria:

1. Patient with exogenous exposure to steroids
2. Ongoing pregnancy
3. Severe comorbid conditions that may interfere with the study.

Where it's running

• Post Graduate Institute of Medical Sciences
  Chandigarh, India Recruiting

Study contacts

• Study coordinator: Rama Walia, DM, Endocrinology
• Email: ramawaliapgimer@gmail.com
• Phone: +911722754757

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.