Condition

COPD Exacerbation clinical trials and research

• 15Clinical trials
• 12Countries

Newest COPD Exacerbation clinical trials

All recruiting trials (15)

• Early detection of COPD flares with a home monitoring device

  A home-monitoring device called RespirAI is being tested to see if it can alert adults with COPD about coming flare-ups before they happen.

  Recruiting RespirAI US Inc · Omaha, Nebraska · NCT07554352

• High-intensity resistance training after a COPD exacerbation

  This project tests whether a short program of high-load, low-repetition leg-strength training helps people recovering from a COPD flare rebuild strength and exercise tolerance with less breathlessness than standard endurance exercise.

  Recruiting Istituti Clinici Scientifici Maugeri SpA · Lumezzane, Brescia · NCT07302425

• Improving oral care to prevent pneumonia in COPD patients in the ICU

  This study is testing if better oral care can help prevent pneumonia in COPD patients who are in the ICU.

  Recruiting Assiut University · Asyut · NCT06691399

• Support for COPD patients after hospital discharge

  This study tests whether giving COPD patients special rescue packs with medication and a management plan after they leave the hospital can help them stay healthier and avoid going back to the hospital.

  Recruiting at 10 sites Phase 3 Guy's and St Thomas' NHS Foundation Trust · Barnsley and 33 other locations · NCT06347536

• Observing patients with severe COPD exacerbations in the ICU

  This study looks at patients with severe COPD flare-ups in the ICU to learn more about their health, treatments, and chances of recovery.

  Recruiting at 4 sites Versailles Hospital · Grenoble and 3 other locations · NCT06257329

• Effects of CPAP on COPD and Sleep Apnea Overlap Syndrome

  This study is testing if using a CPAP machine can help people with both COPD and sleep apnea feel better and reduce health problems over a year.

  Recruiting at 15 sites University Hospital, Angers · Angers and 14 other locations · NCT05958563

• Comparing new nasal interface with standard cannula for COPD patients

  This study is testing a new type of nasal breathing device against a standard one to see which helps people with COPD feel better during a flare-up.

  Recruiting at 2 sites Larissa University Hospital · Athens and 1 other locations · NCT05829083

• Using machine learning to predict outcomes for COPD patients in Hong Kong

  This study is trying to use computer technology to predict which COPD patients in Hong Kong might need to go back to the hospital soon after being discharged, so they can get better care.

  Recruiting Chinese University of Hong Kong · Hong Kong, New Territories · NCT05825014

• Home-based pulmonary rehabilitation for severe COPD management

  This study is testing if a home-based rehabilitation program can help people with severe COPD have fewer flare-ups and hospital visits while improving their breathing and strength.

  Recruiting Saglik Bilimleri Universitesi · Istanbul · NCT05738720

• Titrated versus standard oxygen for prehospital treatment of COPD exacerbations

  This trial tests whether giving oxygen adjusted to keep blood oxygen (SpO₂) at 88–92% instead of using 100% oxygen during prehospital treatment of adults 40 and older with suspected COPD exacerbations lowers 30-day death.

  Recruiting Phase 4 Central Denmark Region · Aarhus N · NCT05703919

• Monitoring COPD Exacerbations Without Contact

  This study tests if a special device can help people with COPD spot early signs of flare-ups while they sleep, so they can manage their condition better.

  Recruiting Life Detection Technologies · London · NCT05598983

• Management of severe COPD through a multidisciplinary approach

  This study is testing a team-based approach to care for people with severe COPD who have been hospitalized to see if it helps them feel better and have fewer flare-ups compared to regular treatment.

  Recruiting Vastra Gotaland Region · Gothenburg, VGR · NCT04860375

• Home ventilation for COPD patients

  This study is testing if different types of home breathing support can help COPD patients who have trouble breathing after a hospital stay avoid going back to the hospital and live longer.

  Recruiting Clinact · Paris, Île-de-France Region · NCT03890224

• Nasal high-flow therapy for COPD exacerbations

  This study is testing if nasal high-flow therapy can help hospitalized patients with COPD recover better from flare-ups compared to standard care.

  Recruiting at 3 sites University Medical Center Groningen · Arnhem and 2 other locations · NCT03564236

• Management of Chronic Obstructive Pulmonary Disease in Switzerland

  This study looks at how to better manage and treat people with COPD in Switzerland by checking their lung health and smoking history.

  Recruiting Cantonal Hospital, Baselland · Liestal, Basel-Landschaft · NCT02065921

Related topics

Quick answers

How many COPD Exacerbation clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in France (3 trials), United Kingdom (2 trials), United States (1 trial), Denmark (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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